Abstract
This article provides an in-depth guide to 4,4′-Diaminobenzenesulphanilide, also known as CAS 16803-97-7. It covers the chemical properties, synthesis methods, applications, safety considerations, and regulatory information surrounding this compound. The guide aims to offer a comprehensive understanding of 4,4′-Diaminobenzenesulphanilide, making it an essential resource for researchers, chemists, and anyone interested in this chemical.
Introduction to 4,4′-Diaminobenzenesulphanilide
4,4′-Diaminobenzenesulphanilide, with the chemical formula C12H10N2O2S, is a synthetic organic compound that belongs to the class of sulphonamides. It is commonly used in the pharmaceutical industry for the synthesis of various drugs. This guide will delve into the details of this compound, including its structure, properties, and uses.
Chemical Properties of 4,4′-Diaminobenzenesulphanilide
4,4′-Diaminobenzenesulphanilide is a white to off-white crystalline solid that is soluble in organic solvents such as ethanol and acetone. It has a melting point of approximately 224-226°C and a boiling point of around 460°C. The compound is characterized by its aromatic ring structure, which contains two amino groups and a sulphonamide group. These functional groups contribute to its chemical reactivity and potential applications.
Synthesis of 4,4′-Diaminobenzenesulphanilide
The synthesis of 4,4′-Diaminobenzenesulphanilide typically involves the reaction of aniline with sulphanilic acid. This reaction can be carried out through various methods, such as the nitration of aniline followed by the reaction with sulphanilic acid, or the direct reaction of aniline with sulphanilic acid in the presence of a catalyst. The choice of synthesis method can affect the purity and yield of the final product.
Applications of 4,4′-Diaminobenzenesulphanilide
4,4′-Diaminobenzenesulphanilide is primarily used in the pharmaceutical industry for the synthesis of sulfonamide drugs, which are known for their antibacterial properties. These drugs are used to treat various bacterial infections. Additionally, the compound is used in the production of dyes, pigments, and other organic compounds.
Safety Considerations for 4,4′-Diaminobenzenesulphanilide
Handling 4,4′-Diaminobenzenesulphanilide requires appropriate safety measures due to its potential toxicity. The compound is harmful if inhaled, ingested, or absorbed through the skin. It is important to wear protective equipment, such as gloves and goggles, when working with this substance. Proper ventilation and adherence to safety protocols are crucial to minimize the risk of exposure.
Regulatory Information for 4,4′-Diaminobenzenesulphanilide
4,4′-Diaminobenzenesulphanilide is subject to regulatory controls in many countries. The compound is classified as a hazardous substance, and its handling, storage, and transportation are governed by specific regulations. Compliance with these regulations is essential to ensure the safety of workers and the environment.
Conclusion
In conclusion, 4,4′-Diaminobenzenesulphanilide, CAS 16803-97-7, is a significant compound with a variety of applications in the pharmaceutical and chemical industries. This guide has provided an overview of its chemical properties, synthesis methods, applications, safety considerations, and regulatory information. Understanding these aspects is crucial for researchers, chemists, and anyone involved in the handling or use of this compound.
Keywords: 4,4′-Diaminobenzenesulphanilide, CAS 16803-97-7, sulphonamide, synthesis, applications, safety, regulatory information
