Abstract
This article provides an in-depth overview of Guanidine Thiocyanate, CAS 593-84-0, a chemical compound with a wide range of applications. It covers its physical and chemical properties, synthesis methods, uses in various industries, safety and health considerations, and regulatory information. By exploring these aspects, the article aims to offer a comprehensive understanding of this chemical and its significance in modern society.
Introduction to Guanidine Thiocyanate CAS 593-84-0
Guanidine Thiocyanate, with the chemical formula C2H4N4SCN, is a colorless crystalline solid that is highly soluble in water. It is commonly used in the synthesis of pharmaceuticals, dyes, and agrochemicals. This compound is also employed in analytical chemistry for its ability to form stable complexes with metal ions. In this article, we will delve into the various aspects of Guanidine Thiocyanate, including its physical and chemical properties, synthesis, applications, and safety considerations.
Physical and Chemical Properties of Guanidine Thiocyanate
Guanidine Thiocyanate is a white to pale yellow crystalline solid that is odorless and has a melting point of approximately 285°C. It is highly soluble in water, with a solubility of about 100 g per 100 mL at 20°C. The compound is also soluble in organic solvents such as alcohol, acetone, and ether. Its chemical properties include the ability to form stable thiocyanate complexes with metal ions, which makes it useful in analytical chemistry.
Synthesis of Guanidine Thiocyanate
The synthesis of Guanidine Thiocyanate involves several methods, including the reaction of guanidine hydrochloride with thiocyanic acid, the reaction of guanidine with thiocyanate salts, and the reaction of guanidine with thiocyanate esters. The most common method is the reaction of guanidine hydrochloride with thiocyanic acid, which produces the desired compound in high yield. This synthesis method is not only efficient but also environmentally friendly, as it does not require the use of harsh conditions or toxic reagents.
Applications of Guanidine Thiocyanate
Guanidine Thiocyanate finds extensive use in various industries. In the pharmaceutical industry, it is used as a starting material for the synthesis of drugs, including antiviral agents and cancer therapeutics. In the dye industry, it is employed in the production of azo dyes, which are widely used in textiles and plastics. Additionally, it is used in agrochemicals for the synthesis of herbicides and insecticides.
Health and Safety Considerations
Guanidine Thiocyanate is considered hazardous due to its potential to cause irritation to the skin, eyes, and respiratory system. It is also toxic if ingested or inhaled. Therefore, proper handling and storage are essential to prevent accidents. Workers handling this chemical should wear appropriate personal protective equipment, such as gloves, goggles, and respirators. In case of exposure, immediate medical attention should be sought.
Regulatory Information
Guanidine Thiocyanate is subject to regulations in many countries due to its potential hazards. The European Union has classified it as a hazardous substance, and it is listed under the REACH (Registration, Evaluation, Authorisation, and Restriction of Chemicals) regulation. In the United States, it is regulated under the Toxic Substances Control Act (TSCA) and the Occupational Safety and Health Administration (OSHA) has established permissible exposure limits for workplace exposure.
Conclusion
Guanidine Thiocyanate, CAS 593-84-0, is a versatile chemical compound with a wide range of applications in various industries. Its physical and chemical properties, synthesis methods, and uses in pharmaceuticals, dyes, and agrochemicals highlight its importance in modern society. However, its potential hazards necessitate careful handling and adherence to regulatory guidelines. By understanding the various aspects of Guanidine Thiocyanate, we can appreciate its significance while ensuring its safe and responsible use.
Keywords
Guanidine Thiocyanate, CAS 593-84-0, chemical properties, synthesis, applications, health and safety, regulatory information
