Levomefolate Calcium (CAS 151533-22-1): Comprehensive User Guide
Table of Contents
1. Product Overview & Specifications
Levomefolate Calcium (CAS 151533-22-1)
A bioactive form of folate (Vitamin B9) with superior stability and bioavailability compared to synthetic folic acid.
Technical Parameters
| Parameter | Details |
|---|---|
| CAS Number | 151533-22-1 |
| Molecular Formula | C20H23CaN7O6 |
| Appearance | White to off-white crystalline powder |
| Purity | ≥98% (HPLC) |
| Solubility | Soluble in water (50 mg/mL) |
Comparative Analysis
| Feature | Levomefolate Calcium | Folic Acid | 5-MTHF |
|---|---|---|---|
| Bioavailability | 100% active form | Requires conversion | 70-80% active |
| Thermal Stability | Stable up to 150°C | Degrades at 100°C | Stable up to 120°C |
| pH Tolerance | 2.0-8.0 | 6.0-7.0 | 3.0-7.5 |
2. Key Applications & Use Cases
Pharmaceutical Applications
- Prenatal vitamins for neural tube defect prevention
- Antidepressant adjuvants in methylation therapy
- Cardiovascular health formulations
Nutraceutical Uses
- Dietary supplements for MTHFR gene mutation carriers
- Sports nutrition for homocysteine regulation
- Aging population nutritional support
3. Industry Applications
Case Study 1: Pharmaceutical Tablet Manufacturing
Challenge: Develop heat-stable prenatal tablets with 800μg folate equivalent.
Solution: Used levomefolate calcium at 1:1.7 ratio to folic acid.
Result: 98% potency retention after 24 months at 25°C.
Case Study 2: Liquid Supplement Formulation
Challenge: Create acidic (pH 3.5) energy drink with bioavailable folate.
Solution: 250μg levomefolate calcium per serving.
Result: Zero precipitation after 18-month shelf life.
4. Verified Customer Success Stories
PharmaHealth Inc. (USA)
Project: Prenatal vitamin line expansion
Implementation: 1000kg annual procurement since 2021
Outcome: 40% market share increase in premium prenatal segment
NeuroWellness Group (EU)
Project: Methylation-support supplements
Implementation: Custom 500mg capsules
Outcome: 90% customer-reported mood improvement in 8 weeks
5. Request Custom Formulation Support
Contact our technical team for formulation optimization, regulatory compliance support, and bulk pricing:
- Email: info@vivalr.com
- Tel: (86) 15866781826
Why Choose Us:
– ISO 9001-certified production
– Custom particle size distributions (10-200μm)
– Full regulatory documentation support
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