Procaterol Hemihydrate (CAS 81262-93-3): Comprehensive User Guide
Table of Contents
1. Product Overview & Specifications
Procaterol Hemihydrate (CAS 81262-93-3) is a selective β2-adrenergic receptor agonist used primarily in bronchodilation therapies. Below are its key specifications:
| Parameter | Details |
|---|---|
| CAS Number | 81262-93-3 |
| Molecular Formula | C₁₆H₂₂N₂O₃·½H₂O |
| Molecular Weight | 307.36 g/mol (anhydrous basis) |
| Purity | ≥98% (HPLC) |
| Appearance | White to off-white crystalline powder |
| Solubility | Soluble in DMSO, ethanol; slightly soluble in water |
Comparative Analysis
| Feature | Procaterol Hemihydrate | Similar Agonists |
|---|---|---|
| Receptor Selectivity | High β2 specificity | Moderate selectivity |
| Half-life | 5-8 hours | 2-4 hours |
| Thermal Stability | Stable up to 150°C | Degrades above 100°C |
2. Key Applications & Uses
Medical Applications
- Asthma management via bronchodilation
- COPD (Chronic Obstructive Pulmonary Disease) treatment
- Prevention of exercise-induced bronchospasm
Research Applications
- Study of β2-adrenergic signaling pathways
- Drug delivery system optimization
- In vitro toxicity profiling
3. Usage Guidelines & Best Practices
Formulation Tips
- Store at 2-8°C in airtight containers
- For aqueous solutions, use pH 4.5-5.5 buffers
- Avoid exposure to strong oxidizers
Safety Protocols
- Use PPE (gloves, goggles) during handling
- LD₅₀ (oral, rat): 1,250 mg/kg
- ECHA Classification: H319 (Eye irritation)
4. Case Studies
Case 1: Inhalation Solution Development
A pharmaceutical company achieved 30% faster bronchodilation onset by optimizing Procaterol Hemihydrate (0.02% w/v) in nebulizer formulations.
Case 2: Receptor Binding Study
Researchers used 10 μM concentrations to demonstrate 89% β2 receptor occupancy within 2 minutes in murine models.
5. Client Success Stories
Client A: EuroPharma Solutions
Challenge: Needed GMP-grade material for Phase III trials
Solution: Supplied 25 kg batches with 99.7% purity
Result: Accelerated regulatory approval by 6 months
Client B: University of Stockholm
Challenge: Required stable isotope-labeled analogs
Solution: Custom-synthesized ¹³C-labeled Procaterol
Result: Enabled breakthrough PK/PD modeling study
6. Request a Quote
Contact our team for technical specifications, pricing, or custom synthesis requirements:
- Email: info@vivalr.com
- Phone: (86) 15866781826
Why Choose Us?
- ISO 9001:2015 certified production
- Bulk quantities (up to 500 kg/month)
- Global shipping with cold-chain support
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