2-Amino-5-chloropyrazine

Comprehensive Guide to 2-Amino-5-chloropyrazine: Uses, Case Studies, and Supplier Insights

1. Product Overview & Specifications

2-Amino-5-chloropyrazine (CAS 17497-97-9) is a heterocyclic organic compound with molecular formula C₄H₄ClN₃ and molecular weight 129.55 g/mol. Key parameters:

2. Applications of 2-Amino-5-chloropyrazine

Primary industrial uses include:

• Pharmaceutical Intermediate: Synthesis of kinase inhibitors (e.g., anti-cancer drugs)
• Agrochemicals: Building block for herbicides and fungicides
• Material Science: Precursor for conductive polymers

3. Usage Guidelines & Best Practices

Recommended protocols:

• Handle under nitrogen atmosphere for moisture-sensitive reactions
• Use anhydrous solvents (DMF, THF) for optimal coupling efficiency
• Typical reaction temperature: 0-40°C

4. Industry Case Studies

Case 1: A top-10 pharma company achieved 92% yield in synthesizing Bruton’s tyrosine kinase (BTK) inhibitor using 2-amino-5-chloropyrazine as key intermediate.

Case 2: European agrochemical producer developed broad-spectrum fungicide with 40% lower ecotoxicity than market benchmarks.

5. Verified Customer Success Stories

Customer A: (Confidential) Chinese CRO reduced lead optimization time from 14 to 9 weeks through optimized pyrazine derivatives.

Customer B: US materials startup patented novel OLED materials using 2-amino-5-chloropyrazine building blocks.

6. How to Inquire or Purchase

Contact our technical team for:

• Custom synthesis (1g to 100kg scale)
• Regulatory support (REACH, TSCA compliant)
• Sample requests (5g free for qualified buyers)

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