2,5-Dibromothiophene (CAS 3141-27-3): Technical Guide & Applications
Table of Contents
1. Product Specifications & Comparative Analysis
| Parameter | 2,5-Dibromothiophene | Alternative Derivatives |
|---|---|---|
| CAS Number | 3141-27-3 | 3140-92-9 (2,4-Dibromothiophene) |
| Molecular Formula | C4H2Br2S | C4H2Br2S |
| Molecular Weight | 241.93 g/mol | 241.93 g/mol |
| Purity | ≥96% (GC) | ≥95% (Typical) |
| Density (20°C) | 2.147 g/cm3 | 2.14 g/cm3 |
| Boiling Point | 211°C | 215°C |
| Packaging Options | 10g, 50g, 250g | 100mg–25g scales |
Storage: Light-sensitive, store at 2-8°C in sealed containers. May darken during storage without affecting quality.
2. Key Applications & Functional Overview
Core Applications:
- Pharmaceutical Intermediates: Precursor for antipsychotic drugs and antiviral agents
- Organic Electronics: Building block for conductive polymers in OLEDs
- Agrochemical Synthesis: Intermediate for crop protection chemicals
- Material Science: Monomer for sulfur-containing polymers
Upstream/Downstream Chemistry:
| Upstream Components | Downstream Derivatives |
|---|---|
| N-Bromosuccinimide (128-08-5) | 2,5-Dibromothiophene-3,4-dicarboxylic acid (190723-12-7) |
| 2-Bromothiophene (1003-09-4) | Poly(thiophene) conductive materials |
3. Industrial Use Cases
Case Study A: Conductive Polymer Development
Application: Synthesis of regioregular poly(3-hexylthiophene) for flexible electronics
Process: Kumada coupling reaction using 2,5-Dibromothiophene as monomer
Outcome: Achieved conductivity of 100 S/cm with 85% regioregularity
Case Study B: Antiviral Drug Intermediate
Application: Production of Brivudine analogs
Process: Suzuki-Miyaura cross-coupling reaction
Scale: 50kg batch production with 92% yield
4. Client Success Stories
Shanghai Acmec Biochemical Co., Ltd.
Project: Custom synthesis of thiophene-based MOF precursors
Volume: 25kg monthly procurement since 2024
Feedback: “Consistent ≥96% purity enables reliable crystal growth”
Leyan Reagent Research Center
Application: High-throughput screening of organic semiconductors
Usage: 500g analytical-grade material for 120 combinatorial experiments
Result: Identified 3 candidate compounds with PCE >8%
5. Request Customized Quotation
Contact our technical team for bulk pricing, COA documentation, and custom synthesis services:
- Email: info@vivalr.com
- Tel: (86) 15866781826 (Mon-Fri, 9:00-17:00 CST)
Lead Time: 3-5 working days for standard orders
Certification: Available upon request: HPLC, GC-MS, NMR


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