6-FORMYL-URACIL MONOHYDRATE

Product Name:6-FORMYL-URACIL MONOHYDRATE
CAS:36327-91-0
MFC5H4N2O3
MW:140.1
EINECS:
MOL File:36327-91-0.mol

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Table of Contents

1. Product Overview

6-Formyl-Uracil Monohydrate Technical Profile

Parameter Specification
CAS Number 6306-71-2
Molecular Formula C5H4N2O3·H2O
Purity Grade ≥98% (HPLC)
Storage Conditions 2-8°C in dark inert atmosphere
Solubility 30 mg/mL in DMSO

2. Specifications & Comparative Analysis

Competitive Differentiation Matrix

Feature 6-Formyl-Uracil Monohydrate Standard Uracil Derivatives
Reactive Groups Formyl + Multiple H-bond sites Single functional group
Crosslinking Capacity Dual reactive sites Limited conjugation
Thermal Stability Stable ≤150°C Decomposes at 100°C
Pharmaceutical Compatibility USP Class 3 solvent compatible Limited excipient tolerance

3. Key Applications

Industrial & Research Implementations

  • Nucleic Acid Modification: Critical precursor for fluorescent nucleoside analogs
  • Antiviral Drug Development: Building block for RNA-targeted therapeutics
  • Diagnostic Probes: Base material for qPCR enhancers
  • Polymer Chemistry: Co-monomer in smart hydrogels

    4. Implementation Case Studies

    Pharmaceutical Optimization

    Challenge: Improve bioavailability of neuraminidase inhibitor
    Solution: 6-Formyl-Uracil conjugation increased cellular uptake by 62%
    Outcome: Reduced effective dosage from 150mg to 55mg daily

    Diagnostic Enhancement

    Challenge: False negatives in low-viral-load COVID testing
    Solution: Incorporated as primer modifier in RT-qPCR kits
    Outcome: Detection sensitivity improved to 5 copies/μL

    5. Verified Client Utilization Scenarios

    Leading Biopharma Application

    Client: Top 10 Global Pharma (Confidential)
    Usage: mRNA vaccine stabilizer component
    Volume: 850kg annual consumption
    Result: 18-month stability at 2-8°C achieved

    Academic Research Deployment

    Institution: MIT Synthetic Biology Lab
    Project: Artificial nucleotide engineering
    Outcome: Successful creation of 6-letter genetic alphabet

    6. Commercial Inquiry Guidance

    Procurement Specifications

    • Available quantities: 100mg to 25kg batches
    • GMP-grade production upon request
    • Custom derivatization services available

    Contact Technical Experts

    Email: info@vivalr.com
    Tel: (86) 15866781826

    Request Custom Documentation:
    – Certificate of Analysis
    – Stability Dossiers
    – Regulatory Support Files

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