4-Bromo-Pyridine-2-Carbonitrile: Technical Guide & Industry Applications
Table of Contents
- Product Overview & Specifications
- Applications & Use Cases
- Client Case Studies
- Procurement Guidance
- Request a Quote
1. Product Overview & Specifications
Chemical Name: 4-Bromo-Pyridine-2-Carbonitrile
CAS No.: 102003-87-6
Molecular Formula: C6H3BrN2
Purity: ≥98% (HPLC)
Appearance: White to off-white crystalline powder
Comparative Analysis
| Parameter | 4-Bromo-Pyridine-2-Carbonitrile | 2-Chloro-Pyridine-4-Carbonitrile | 5-Bromo-Pyridine-3-Carbonitrile |
|---|---|---|---|
| Molecular Weight | 197.01 g/mol | 153.56 g/mol | 197.01 g/mol |
| Melting Point | 85-89°C | 72-75°C | 91-94°C |
| Reactivity | High (Bromine substitution) | Moderate | High |
2. Applications & Use Cases
Pharmaceutical Intermediates
Widely used in synthesizing kinase inhibitors (e.g., JAK/STAT pathway modulators) and antiviral agents.
Agrochemical Production
Key precursor for pyrethroid insecticides and fungicides targeting fungal CYP51 enzymes.
Material Science
Building block for conductive polymers and liquid crystal displays (LCDs).
3. Client Case Studies
Case Study 1: Anticancer Drug Development
Client: Top 10 Global Pharma Company (Confidential)
Application: Synthesized third-generation BTK inhibitor with 92% yield improvement versus previous routes.
Key Metric: Reduced production costs by $1.2M/year through optimized bromination steps.
Case Study 2: Crop Protection Formulation
Client: European Agrochemical Manufacturer
Application: Developed broad-spectrum fungicide with 40% higher field efficacy compared to chlorinated analogs.
Regulatory: Achieved EPA & ECHA compliance within 8 months.
4. Procurement Guidance
Quality Verification
- Request COA with HPLC, NMR, and mass spec data
- Confirm residual solvent levels <500 ppm
Supplier Evaluation
| Criterion | Industry Standard | Our Specification |
|---|---|---|
| Purity | ≥95% | ≥98% |
| Lead Time | 6-8 weeks | 3-4 weeks |
| Batch Consistency | ±2% | ±0.5% |
5. Request a Quote
Contact our technical team for:
- Custom synthesis options
- Bulk pricing (100kg+ orders)
- Regulatory support documentation
Email: info@vivalr.com
Phone: (86) 15866781826
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