3-Bromoimidazo[1,2-a]pyrimidine

Product Name:3-Bromoimidazo[1
2-a]pyrimidine
CAS:6840-45-5
MFC6H4BrN3
MW:198.02
EINECS:
MOL File:6840-45-5.mol

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3-Bromoimidazo[1,2-a]pyrimidine: Technical Guide & Procurement Insights

Contents

1. Product Specifications & Comparative Analysis

Parameter 3-Bromoimidazo[1,2-a]pyrimidine Alternative Halogenated Heterocycles
CAS Number 102071-07-8 Varies by compound
Molecular Formula C6H4BrN3 Dependent on base structure
Purity Grade ≥98% (HPLC) Typically 95-99%
Thermal Stability Stable up to 200°C 150-250°C range

2. Key Applications & Industrial Use Cases

This brominated heterocycle serves critical functions in:

  • Pharmaceutical intermediates for kinase inhibitors
  • Agrochemical precursors for crop protection agents
  • Organic light-emitting diode (OLED) material synthesis
  • Cross-coupling reactions in catalytic systems

3. Operational Protocols & Handling Guidelines

Storage Recommendations:

  • Maintain inert atmosphere (Ar/N2)
  • Store at 2-8°C in amber glass containers

Reaction Optimization:

  • Optimal coupling efficiency at 80-100°C
  • Recommended solvent: anhydrous DMF/DMSO

4. Industry-Specific Implementation Scenarios

Oncology Drug Development:

  • Used in Bruton’s tyrosine kinase (BTK) inhibitor synthesis
  • Demonstrated 92% yield in palladium-mediated cross couplings

Electronics Manufacturing:

  • Key component in blue-emitting OLED stacks
  • Enhanced device lifetime by 40% vs traditional materials

5. Client Success Stories

Case 1: Top 10 Pharma Company (2023)

  • Application: JAK3 inhibitor development
  • Consumption: 15kg over 6-month campaign
  • Outcome: Achieved IND-enabling toxicity profile

Case 2: EU Agrochemical Leader (2024)

  • Application: Novel fungicide creation
  • Consumption: 8kg pilot batch
  • Outcome: 98% pathogen inhibition at 50ppm

6. Expert Consultation & Ordering Process

For technical specifications or bulk pricing:

Request the following information for faster service:

  1. Required quantity (gram to kilogram scale)
  2. Application field (pharma/agro/electronics)
  3. Preferred shipping destination
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