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Specialized inDicyclohexano-18-crown-6 CAS 16069-36-6and related product development and production

Chemical Name: Dicyclohexano-18-crown-6
CAS No.: 16069-36-6
Molecular Fomula: C20H36O6
Molecular weight: 372.5
Appearance: White to slightly beige crystalline solid
Assay: 98.0%

Samples: Available / Stock: Sufficient
Estimated delivery time: 3-5 days

Dicyclohexano-18-crown-6 (CAS 16069-36-6): Comprehensive Product Guide

Table of Contents

1. Product Specifications & Comparative Analysis

Parameter Dicyclohexano-18-crown-6 Standard Crown Ethers
CAS Number 16069-36-6 Varies by type
Molecular Formula C20H36O6 Typically C12-C24
Molecular Weight 372.50 g/mol 300-400 g/mol
Appearance White to off-white crystalline powder Colorless to pale yellow
Melting Point 47-50°C 30-100°C
Solubility Soluble in organic solvents, limited water solubility Similar profile
Selectivity High affinity for potassium ions Ion-specific variations

2. Key Applications & Industrial Uses

Core Functional Capabilities:

  • Phase-transfer catalysis in organic synthesis
  • Selective ion recognition and separation
  • Enhancement of reaction kinetics in nucleophilic substitutions
  • Metal ion complexation in analytical chemistry

Industry-Specific Implementations:

  • Pharmaceutical Manufacturing: Chiral resolution in API production
  • Chemical Synthesis: Potassium-mediated coupling reactions
  • Analytical Chemistry: Ion-selective electrode components
  • Nuclear Technology: Strontium isotope separation

3. Operational Best Practices

Optimal Handling Protocols:

  • Storage: Maintain at 2-8°C in airtight containers
  • Concentration: Use 0.1-5 mol% in catalytic applications
  • Solvent Systems: Compatible with THF, DCM, and toluene
  • Safety: Use PPE due to skin/eye irritation potential

Performance Optimization:

  • Combine with picric acid for enhanced extraction efficiency
  • Utilize in anhydrous conditions for maximum catalytic activity
  • Implement recycling protocols for cost-sensitive applications

4. Implementation Case Studies

Case 1: Pharmaceutical Intermediate Synthesis

A European pharma company achieved 78% yield improvement in SN2 reactions through 2.4 mol% catalyst loading, reducing reaction time from 18h to 6h.

Case 2: Rare Earth Element Separation

Mining operation achieved 99.2% purity in potassium extraction from brine solutions using custom-formulated crown ether matrices.

5. Client Success Stories

Chemical Manufacturer (Germany):

  • Challenge: Low efficiency in aryl fluoride production
  • Solution: Optimized crown ether/potassium carbonate system
  • Result: 62% cost reduction per kilogram output

University Research Lab (USA):

  • Application: Development of ion-selective sensors
  • Performance: Achieved 10-8 M detection limit for K+
  • Outcome: Published in ACS Analytical Chemistry (2024)

6. Request Customized Solutions

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This is William, CEO of fousi chemical Chemical Co., Ltd.

Welcome to visit our factory . As the top chemical manufacturer, we have been striving for product quality, innovation , R&D, and customer service for the past 7 years. In the next 10 years or even longer, we are committed to becoming the most reliable chemical supplier in the world , creating a well-known international brand trusted by customers, with the spirit of “one meter wide, ten thousand meters deep”, we continue to focus on product research and development, continue to focus on customer service, continue to improve the supply chain service system, to create a professional chemical supply service team, to achieve win-win long-term cooperation. Please feel free to contact us if you have any questions.

Drug impurities to intermediates. Years of expertise.

Experience in the synthesis of complex compounds derived from American technology
Focus on the synthesis of difficult compounds
ISO 17034 dual system certification
National high-tech enterprise
5000+ square meters R&D center
A 70+ R&D team led by Chinese and foreign doctors
150 pieces (sets) of R&D equipment, 120+ fume hoods
18 patents

Solid QMS. Offer top-quality products and services.

Through more than ten years of continuous technological innovation and experience accumulation, the team's R&D personnel have established a complete quality management system for CATO, and have successively obtained ISO9001, ISO17034, CNAS and other international certifications.
It has successfully passed on-site inspections from the United States, Australia, Poland, Japan and domestic pharmaceutical company customers and institutions many times, providing high-quality one-stop services for R&D and production of new drugs around the world.

More than 150 sets of equipment to ensure quality.

The emphasis on quality is the basis for our survival and development, and is the most basic requirement for the products and services we provide. CATO has established a scientific, strict and comprehensive quality prevention and assurance system in accordance with international quality standards. Through advanced testing equipment such as GC-MS, chromatograph, nuclear magnetic resonance, scanning electron microscope, and ultraviolet light, quality management is implemented into every aspect of production and operation activities such as raw materials, inventory, production, testing, sales, verification, and training, and "All actions are controlled and traceable" as the work code of conduct for CATO employees.

Over 1000 cases. Synthesize complex compounds.

Currently, CATO serves more than 500 pharmaceutical companies, biotechnology and other companies around the world. Project types cover the entire cycle from pre-clinical to commercialization stages. As of 2020, CATO has delivered more than 1,000 projects in total.
The company has core technologies in key core technology fields such as high-end fluorine chemistry, asymmetric chiral synthesis, glycoside and biological enzyme technology, and continuous microreactors.

About the company

International Standard Chemicals Sell To All Over The World

FAQ

Does it support auditing?

Support, please make an appointment one day in advance. Company address: Room 716, Building 3, Ligao International Garden, No.1222 West Aoti Road, Lixia District, Jinan City, Shandong Province, P.R. China

Whether to provide samples?

Free samples can be provided for low value products, and small packaging specifications can be purchased for high value products.

Delivery time

Under normal circumstances, all items are in stock and will be shipped before 4 o'clock on the same day. Some products are produced to order, depending on the workshop situation and production schedule.

What is the production capacity?

At present, the company's workshop production equipment is mainly based on laboratories and pilot lines, with a maximum daily production capacity of 1.5 tons.

Can additional test indicators be added?

We can provide moisture, UV, IR, HNMR, CNMR, two-dimensional nuclear magnetic spectroscopy, optical rotation detection, elemental analysis, TGA analysis and residue analysis and other related tests to support personalized needs.

Technical direction

In the early stage, our company mainly engaged in drug impurity synthesis and standard product production, with core technologies in chirality, fluorine chemistry, and heterocycles.

Why Chem-iso’s delivery rate is guaranteed to be 99.99%

5000+

square meter R&D center

150+

China(set) of R&D equipment

150+

Fume hood

180+

R&D team

User’evaluation of us

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