Dicyclohexano-18-crown-6 CAS 16069-36-6

Chemical Name: Dicyclohexano-18-crown-6
CAS No.: 16069-36-6
Molecular Fomula: C20H36O6
Molecular weight: 372.5
Appearance: White to slightly beige crystalline solid
Assay: 98.0%

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Dicyclohexano-18-crown-6 (CAS 16069-36-6): Comprehensive Product Guide

Table of Contents

1. Product Specifications & Comparative Analysis

Parameter Dicyclohexano-18-crown-6 Standard Crown Ethers
CAS Number 16069-36-6 Varies by type
Molecular Formula C20H36O6 Typically C12-C24
Molecular Weight 372.50 g/mol 300-400 g/mol
Appearance White to off-white crystalline powder Colorless to pale yellow
Melting Point 47-50°C 30-100°C
Solubility Soluble in organic solvents, limited water solubility Similar profile
Selectivity High affinity for potassium ions Ion-specific variations

2. Key Applications & Industrial Uses

Core Functional Capabilities:

  • Phase-transfer catalysis in organic synthesis
  • Selective ion recognition and separation
  • Enhancement of reaction kinetics in nucleophilic substitutions
  • Metal ion complexation in analytical chemistry

Industry-Specific Implementations:

  • Pharmaceutical Manufacturing: Chiral resolution in API production
  • Chemical Synthesis: Potassium-mediated coupling reactions
  • Analytical Chemistry: Ion-selective electrode components
  • Nuclear Technology: Strontium isotope separation

3. Operational Best Practices

Optimal Handling Protocols:

  • Storage: Maintain at 2-8°C in airtight containers
  • Concentration: Use 0.1-5 mol% in catalytic applications
  • Solvent Systems: Compatible with THF, DCM, and toluene
  • Safety: Use PPE due to skin/eye irritation potential

Performance Optimization:

  • Combine with picric acid for enhanced extraction efficiency
  • Utilize in anhydrous conditions for maximum catalytic activity
  • Implement recycling protocols for cost-sensitive applications

4. Implementation Case Studies

Case 1: Pharmaceutical Intermediate Synthesis

A European pharma company achieved 78% yield improvement in SN2 reactions through 2.4 mol% catalyst loading, reducing reaction time from 18h to 6h.

Case 2: Rare Earth Element Separation

Mining operation achieved 99.2% purity in potassium extraction from brine solutions using custom-formulated crown ether matrices.

5. Client Success Stories

Chemical Manufacturer (Germany):

  • Challenge: Low efficiency in aryl fluoride production
  • Solution: Optimized crown ether/potassium carbonate system
  • Result: 62% cost reduction per kilogram output

University Research Lab (USA):

  • Application: Development of ion-selective sensors
  • Performance: Achieved 10-8 M detection limit for K+
  • Outcome: Published in ACS Analytical Chemistry (2024)

6. Request Customized Solutions

Contact our technical team for application-specific guidance:

Request free technical consultation or sample evaluation.

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