3-Hydroxy-2-nitropyridine

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3-Hydroxy-2-nitropyridine Technical Guide

Table of Contents

Product Specifications

Parameter Value
CAS Number 15128-82-2
Molecular Formula C5H4N2O3
Molecular Weight 140.10 g/mol
Purity Grade ≥97% (HPLC)
Physical Form Yellow crystalline powder
Melting Point 69-71°C
Storage Conditions 2-8°C in airtight container

Applications & Industry Uses

This heterocyclic compound serves as critical intermediate in:

  • Pharmaceutical synthesis (antibiotic precursors)
  • Agrochemical research (pesticide formulations)
  • Coordination chemistry (ligand development)
  • Organic electronics (semiconductor materials)

Technical Parameters Comparison

Variant Purity Solubility Thermal Stability
Standard Grade 97% Soluble in DMSO ≤150°C
Research Grade 99% DMF/EtOH soluble ≤180°C
Custom Halogenated 95% Chlorinated solvents ≤130°C

Operational Guidelines

Critical handling protocols:

  • Use NIOSH-approved respirator with organic vapor cartridge
  • Maintain fume hood airflow ≥100 fpm during processing
  • Incompatible with strong oxidizers/reducing agents
  • pH stabilization range: 6.8-7.2 (aqueous solutions)

Case Studies

Case 1: Pharmaceutical Intermediate Synthesis

Shanghai PharmaTech achieved 22% yield improvement in antibiotic precursor synthesis through optimized nitro-group positioning using 3-Hydroxy-2-nitropyridine (Batch No. HTN-2203).

Case 2: Advanced Material Development

Shenzhen Optoelectronics utilized derivative compounds for OLED layer optimization, achieving 15% efficiency gain in prototype devices (Project Code: LUMI-9Q2024).

Procurement Advisory

For technical specifications sheets or bulk pricing:

  • Email: info@vivalr.com
  • Tel: (86) 15866781826

Include following requirements in RFQ:

  • Required CAS purity level
  • Preferred shipment packaging
  • HS code declaration needs
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