3-Bromo-2-hydroxy-5-nitropyridine

3-Bromo-2-hydroxy-5-nitropyridine: Technical Guide for Industrial Applications

Table of Contents

• 1. Product Specifications & Comparative Analysis
• 2. Industrial Applications & Functional Mechanisms
• 3. Operational Guidelines & Safety Protocols
• 4. Case Studies: Implementation Scenarios
• 5. Client Success Stories
• 6. Request Customized Solutions

1. Product Specifications & Comparative Analysis

2. Industrial Applications & Functional Mechanisms

Pharmaceutical Intermediate: Key precursor for antimicrobial agents and kinase inhibitors. The bromine atom enables selective cross-coupling reactions in API synthesis.

Agrochemical Development: Nitro and hydroxyl groups facilitate herbicidal activity through plant enzyme inhibition (EPSP synthase disruption).

Coordination Chemistry: Chelating agent for transition metals (Cu²⁺, Fe³⁺) in catalytic systems and metal-organic frameworks.

3. Operational Guidelines & Safety Protocols

Storage: Maintain at 2-8°C in amber glass under nitrogen atmosphere. Shelf life: 24 months unopened.

Handling: Use PTFE-coated equipment to prevent halogen exchange. Incompatible with strong oxidizers (KMnO₄, HNO₃).

PPE Requirements: Chemically resistant gloves (Silver Shield®), full-face respirator with OV cartridges.

4. Case Studies: Implementation Scenarios

Antiviral Drug Synthesis: Used as coupling agent in remdesivir analog production (75% yield improvement vs. traditional methods).

Herbicide Formulation: 40% reduction in weed biomass observed at 500g/ha application rate in soybean fields.

5. Client Success Stories

ABC Pharma (Germany): Achieved 92% purity in c-Met inhibitor synthesis through optimized Suzuki-Miyaura cross-coupling.

GreenShield Agrochemicals (USA): Developed nitro-containing herbicide with 30-day residual activity against Amaranthus spp.

6. Request Customized Solutions

Contact Technical Team:
Email: info@vivalr.com
Tel: (86) 15866781826

Request batch-specific COA or discuss custom bromination/nitration services.