BENZYL 2-CHLORO-4-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBOXYLATE

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Benzyl 2-Chloro-4-(trifluoromethyl)pyrimidine-5-carboxylate: Comprehensive User Guide

1. Product Overview & Specifications

Benzyl 2-Chloro-4-(trifluoromethyl)pyrimidine-5-carboxylate (CAS: 210169-20-9) is a high-purity pyrimidine derivative widely used in pharmaceutical and agrochemical synthesis.

Parameter Specification Competitor A Competitor B
Purity ≥98% 95% 97%
Melting Point 60-65°C 58-62°C 63-67°C
Solubility DCM, DMF, THF Limited in THF DMF only

2. Key Applications

This compound serves as a critical intermediate in:

  • Pharmaceuticals: Synthesis of antiviral agents and kinase inhibitors.
  • Agrochemicals: Production of novel fungicides with enhanced efficacy.
  • Chemical Research: Building block for fluorinated heterocycles.

3. Usage Guidelines

Recommended Workflow:

  1. Storage: Keep at -20°C under inert atmosphere
  2. Handling: Use anhydrous conditions for reactions
  3. Typical Reaction: Suzuki coupling (yield: 82-88%)

4. Case Studies

Case 1: Antiviral Drug Intermediate

Used in 7-step synthesis of Remdesivir analog, achieving 40% overall yield improvement compared to traditional routes.

5. Client Success Stories

PharmaTech Solutions

Reduced production costs by 28% through optimized coupling reactions using our compound.

AgroChem Ltd

Developed new-generation fungicide with 99.5% purity using batch consistency from our production.

6. Contact for Custom Solutions

Request tailored specifications or bulk quotes:

Email: info@vivalr.com

Tel: (86) 15866781826

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