3-Iodo-4-aminopyridine

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Comprehensive Guide to 3-Iodo-4-aminopyridine

Table of Contents

1. Product Overview & Specifications

3-Iodo-4-aminopyridine (CAS: 1345459-03-6) is a halogenated aminopyridine derivative widely used in pharmaceutical and organic synthesis. Key parameters:

Parameter Value
Molecular Formula C5H5IN2
Purity ≥98% (HPLC)
Appearance White to off-white crystalline powder
Solubility Soluble in DMSO, methanol

Comparative Analysis

Supplier Purity Packaging
Vivalr ≥98% 1g, 5g, custom
Competitor A ≥95% 5g only

2. Detailed Applications

Pharmaceutical Intermediates

Critical precursor for kinase inhibitors and antiviral agents, enabling precise structural modifications in drug discovery.

Organic Synthesis

Facilitates cross-coupling reactions (e.g., Suzuki-Miyaura) for creating complex heterocyclic compounds.

3. Usage Instructions

Handling Protocols

Store at 2-8°C under inert atmosphere. Use PPE during handling due to light sensitivity.

Reaction Optimization

Typical reaction conditions: 0.1 eq catalyst, 1.2 eq substrate in DMF at 80°C for 6 hours.

4. Application Case Studies

Anticancer Drug Development

Used in synthesizing PARP inhibitors showing 72% tumor growth inhibition in preclinical trials.

OLED Material Research

Key intermediate for electron-transport layers achieving 15% improved luminescence efficiency.

5. Client Success Stories

PharmaTech Solutions

Accelerated lead optimization phase by 40% using our GMP-grade 3-Iodo-4-aminopyridine in kinase inhibitor R&D.

University of Chemical Innovations

Published 3 Nature Chemistry papers on novel C-N coupling methods using this compound as primary substrate.

6. Request a Quote

Contact our technical team for batch-specific COA, pricing, and custom synthesis options:

Email: info@vivalr.com
Tel: (86) 15866781826

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