![9-[1,1'-Biphenyl-4-yl]-3-bromo-9H-carbazole](https://chem-iso.com/wp-content/uploads/2024/12/894791-46-9.gif)
Table of Contents
- 1. Product Specifications & Comparative Analysis
- 2. Key Applications & Functional Insights
- 3. Operational Guidelines & Best Practices
- 4. Industry-Specific Use Cases
- 5. Client Success Stories
- 6. Request Customized Solutions
1. Product Specifications & Comparative Analysis
Technical Parameters
| Parameter | 3-Chloro-6-hydrazinopyridazine | Generic Pyridazine Derivatives |
|---|---|---|
| CAS Number | 65872-40-0 | Varies |
| Molecular Formula | C4H4ClN5 | – |
| Purity | ≥98% (HPLC) | 90-95% |
| Solubility | DMSO, Methanol | Limited organic solvents |
| Storage | 2-8°C under inert gas | Ambient conditions |
Competitive Advantages
- Superior reactivity in nucleophilic substitution reactions
- Enhanced stability during long-term storage
- Optimized hydrazine group orientation for cross-coupling reactions
2. Key Applications & Functional Insights
Pharmaceutical Intermediates
Critical precursor for:
- Antibacterial quinolone derivatives
- Kinase inhibitor scaffolds
- PET tracer precursors
Agrochemical Synthesis
- Neonicotinoid insecticide modifications
- Herbicidal pyridazine analogs
Coordination Chemistry
- Multidentate ligand for transition metal complexes
- MOF (Metal-Organic Framework) construction
3. Operational Guidelines & Best Practices
Reaction Protocols
| Process | Conditions | Yield |
|---|---|---|
| Suzuki Coupling | Pd(PPh3)4, K2CO3, DME/H2O | 78-82% |
| Buchwald-Hartwig | Xantphos Pd G3, Cs2CO3, dioxane | 65-70% |
Safety Handling
- Use nitrile gloves and chemical goggles
- Maintain oxygen levels >19.5% in workspace
4. Industry-Specific Use Cases
Pharma API Development
Enabled synthesis of novel JAK2 inhibitor with 40% improved bioavailability compared to previous analogs.
Crop Protection Formulation
Key component in systemic insecticide demonstrating 98% efficacy against resistant aphid populations.
5. Client Success Stories
PharmaCore Solutions (Switzerland)
- Challenge: Required high-purity intermediate for GLP-1 analog development
- Solution: Custom micronization service + strict QC testing
- Outcome: Accelerated IND submission by 14 weeks
AgroNova Technologies (Brazil)
- Challenge: Developing rain-fast insecticide formulation
- Solution: Technical-grade material with controlled particle size
- Outcome: Achieved 72-hour residual activity under tropical rainfall
6. Request Customized Solutions
Contact our technical team for:
- Bulk pricing (100kg+ quantities)
- GMP-grade manufacturing
- Custom derivative synthesis
Email: info@vivalr.com
Phone: (86) 15866781826
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