2-Chloropyridine-3-sulfonyl chloride: Comprehensive Product Guide
Table of Contents
- 1. Product Overview & Specifications
- 2. Key Applications & Industrial Uses
- 3. Performance Comparison Analysis
- 4. Operational Guidelines & Best Practices
- 5. Industry Application Cases
- 6. Technical Consultation & Quotation
1. Product Overview & Specifications
| Parameter | Specification |
|---|---|
| CAS Number | 6602-54-6 |
| Molecular Formula | C5H3Cl2NO2S |
| Appearance | White to pale yellow crystalline powder |
| Purity | ≥98.5% (HPLC) |
| Melting Point | 89-92°C |
| Storage Conditions | 2-8°C in inert atmosphere |
Comparative Analysis with Similar Reagents
| Feature | 2-Chloropyridine-3-sulfonyl chloride | Pyridine-2-sulfonyl chloride |
|---|---|---|
| Reactivity | High electrophilicity | Moderate |
| Stability | Air-sensitive | Stable |
| Pharma Applications | API intermediates | Limited |
2. Key Applications & Industrial Uses
Widely utilized as sulfonating agent in:
- Pharmaceutical intermediates for antiretroviral drugs
- Agrochemical synthesis (herbicide precursors)
- Polymer modification catalysts
- Ligand synthesis for transition metal complexes
3. Performance Comparison Analysis
Superior characteristics include:
- 30% higher reaction yield vs. analogues
- Reduced byproduct formation (≤2.7%)
- Compatible with Grignard reactions
4. Operational Guidelines
Recommended protocols:
- Maintain N2 atmosphere during handling
- Use anhydrous solvents (THF/DCM)
- Reaction temp: 0-5°C for optimal control
5. Industry Application Cases
Case 1: Antiviral Drug Synthesis
Client: Top 10 Global Pharma Company
Application: Key intermediate for HCV protease inhibitor
Result: 22% yield improvement vs previous process
Case 2: Herbicide Development
Client: EU Agrochem Leader
Application: Sulfonylurea herbicide precursor
Result: Achieved 99.1% purity in final product
Case 3: Polymer Modification
Client: Specialty Materials Manufacturer
Application: Surface functionalization agent
Result: Enhanced thermal stability by 40°C
6. Technical Consultation & Quotation
Contact our chemical engineers for:
- Custom synthesis solutions
- Bulk order pricing (50kg+ quantities)
- Technical documentation (MSDS, COA)
Email: info@vivalr.com
Tel: (86) 15866781826


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