2-Bromothiophene: Technical Guide for Industrial Applications
Table of Contents
1. Product Specifications & Comparative Analysis
| Parameter | 2-Bromothiophene | Thiophene Derivatives* |
|---|---|---|
| CAS Number | 1003-09-4 | Varies by compound |
| Molecular Formula | C4H3BrS | Typically C4H4S variants |
| Molecular Weight | 163.04 g/mol | 84-180 g/mol range |
| Purity | ≥98.0% | 90-99% commercial grades |
| Density (25°C) | 1.684 g/mL | 1.05-1.85 g/mL |
| Boiling Point | 149-151°C | 80-200°C |
| Flash Point | 52°C | 20-80°C |
*General comparison with thiophene-based compounds
2. Key Applications
- Pharmaceutical Intermediate: Critical precursor for Clopidogrel (antiplatelet drug)
- Organic Synthesis: Building block for heterocyclic compounds
- Material Science: Component in conductive polymer research
3. Operational Guidelines
Storage Recommendations
- Temperature: ≤4°C in sealed containers
- Humidity: Maintain <40% RH
- Shelf Life: 24 months under optimal conditions
4. Implementation Case Studies
Case 1: Pharmaceutical Manufacturing
A European API producer achieved 22% yield improvement in Clopidogrel bisulfate synthesis through optimized 2-bromothiophene purification protocols.
Case 2: Specialty Chemicals
Asian research facility developed novel liquid crystal compounds using 2-bromothiophene as key intermediate, achieving 99.2% HPLC purity.
5. Safety & Compliance Protocols
| Hazard Code | Protection Measures | Emergency Response |
|---|---|---|
| T (Toxic) | Full-face respirator Chemical-resistant gloves |
Eye flush (15 min minimum) Containment protocol |
| Xi (Irritant) | Ventilated workspace PPE ensemble |
Skin decontamination Medical monitoring |
6. Contact for Custom Solutions
Request technical documentation or discuss application-specific requirements:
Email: info@vivalr.com
Tel: (86) 15866781826
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