1. Product Overview & Specifications

2-Chloro-4-nitropyridine (CAS 4214-74-8) is a high-purity chemical intermediate with molecular formula C₅H₃ClN₂O₂ and molecular weight 158.54 g/mol. This yellow crystalline powder is widely recognized for its exceptional reactivity in nucleophilic substitution reactions.

2. Key Applications & Industrial Uses

2.1 Pharmaceutical Manufacturing

• Critical intermediate for antiviral agents (e.g., Remdesivir analogs)
• Precursor in kinase inhibitor synthesis

2.2 Agrochemical Production

• Building block for next-generation herbicides
• Key component in fungicide formulations

3. Usage Guidelines & Best Practices

3.1 Handling Procedures

• Store in airtight containers at 2-8°C
• Use dry nitrogen atmosphere for sensitive reactions

3.2 Reaction Optimization

4. Case Study: Pharmaceutical Intermediate Synthesis

Challenge: A leading API manufacturer required high-yield production of 4-aminopyridine derivatives.

Solution: Using our 2-Chloro-4-nitropyridine as starting material:

1. Catalytic hydrogenation (H₂/Pd-C, 50 psi)
2. Selective chlorination (POCl₃, 110°C)

Result: 92% overall yield (vs. 78% with alternative materials)

5. Verified Customer Success Stories

5.1 AgroPharm Solutions (Jiangsu, China)

• Application: Novel triazole fungicide development
• Outcome: Reduced synthesis steps from 5 to 3
• Capacity: 15 MT/month consumption

5.2 PharmaSynth Inc. (Hyderabad, India)

• Application: COVID-19 therapeutic candidates
• Result: 40% cost reduction in lead compound
• Scale: 8.2 MT batch production

6. Technical Support & Inquiry

Our chemical engineering team provides:

• Custom synthesis protocols
• Scale-up assistance (lab to production)
• Regulatory documentation support

Contact our specialists:

Email: info@vivalr.com

Tel: (86) 15866781826