2-Chloro-3-Methylpyrazine: Comprehensive Technical Guide

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1. Product Specifications & Comparative Analysis

Parameter 2-Chloro-3-Methylpyrazine Analogous Compounds
CAS Registry 95-58-9 112930-94-6 (5-Bromo variant)
Molecular Formula C5H5ClN2 C5H4BrClN2
Molecular Weight 128.56 g/mol 207.46 g/mol
Synthetic Routes • Chlorination of 2-hydroxy-3-methylpyrazine
• Modified Knoevenagel condensation processes

2. Industrial Applications

This heterocyclic compound serves critical functions in:

  • Pharmaceutical Intermediate: Core component in antihypertensive drug synthesis
  • Agrochemical Production: Precursor for next-generation crop protection agents
  • Flavor Chemistry: Key element in creating roasted flavor profiles
  • Polymer Science: Cross-linking agent for specialty resins

3. Operational Protocols

Handling Requirements:

  • Storage: Nitrogen atmosphere at 2-8°C
  • Reactivity: Compatible with THF, DMF, and chlorinated solvents
  • Safety: PPE including neoprene gloves and vapor respirators required

4. Implementation Case Studies

Case 1: Pharmaceutical Scale-Up
European API manufacturer achieved 92% yield improvement through optimized chlorination sequencing.

Case 2: Specialty Polymer Development
Japanese materials science team created heat-resistant adhesives with 40% enhanced thermal stability.

5. Client Success Stories

Shanghai Yuanye Bio-Tech:
Implemented continuous flow chemistry for high-purity batch production (≥99.2% HPLC purity).

Shenzhen High-Safety Biotech:
Developed analytical standards meeting ISO 17025 requirements for regulatory submissions.

6. Commercial Inquiry Process

Technical specifications and pricing available through our engineering team:

Contact Method Details
Chemical Engineering Support info@vivalr.com
Procurement Coordination (86) 15866781826
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