2,6-Difluoropyridine-3-boronic Acid: Technical Guide & Application Insights
Contents
- 1. Product Specifications & Comparative Analysis
- 2. Functional Applications & Industry Use-Cases
- 3. Operational Best Practices & Synthesis Workflows
- 4. Verified Client Implementations
- 5. Commercial Inquiry & Technical Support
1. Product Specifications & Comparative Analysis
| Parameter | 2,6-Difluoropyridine-3-boronic Acid | Generic Boronic Acids |
|---|---|---|
| CAS Number | 944401-80-5 | Varies |
| Molecular Formula | C5H4BF2NO2 | R-B(OH)2 |
| Purity Grade | ≥98% (HPLC) | 90-95% |
| Suzuki Coupling Efficiency | High (＞90% yield) | Moderate (70-85%) |
2. Functional Applications & Industry Use-Cases
Core Functional Areas:
- Pharmaceutical Intermediates: Key building block for kinase inhibitors & antiviral agents
- Material Science: Precursor for OLED electron-transport layers
- Agrochemicals: Synthesis of next-gen herbicides with fluorinated pyridine cores
3. Operational Best Practices & Synthesis Workflows
Standard Reaction Conditions:
| Reaction Type | Catalyst System | Optimal Temperature |
|---|---|---|
| Suzuki-Miyaura | Pd(PPh3)4 (1 mol%) | 80-100°C |
| Chan-Lam | Cu(OAc)2 (20 mol%) | RT-50°C |
4. Verified Client Implementations
Case 1: Anticancer Drug Development
Client: Top 10 Global Pharma Company
Application: Synthesized Bruton’s tyrosine kinase (BTK) inhibitor candidate
Scale: 15 kg batch production
Yield Improvement: 22% vs. traditional boronic esters
Case 2: Flexible OLED Manufacturing
Client: Asian Display Materials Leader
Application: Created hole-blocking layer for foldable screens
Performance: 18% efficiency gain in device lifetime
5. Commercial Inquiry & Technical Support
Request Custom Synthesis or Bulk Pricing:
Email: info@vivalr.com
Phone: (86) 15866781826
Why Choose Our Supply?
- Strict QC: ISO 9001-certified production
- Global Logistics: DDP terms available
- Technical Docs: COA/MSDS upon request
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