2-Amino-4-methyl-5-bromopyrimidine: Comprehensive User Guide
Table of Contents
1. Product Overview & Specifications
2-Amino-4-methyl-5-bromopyrimidine (CAS 849550-91-2) is a brominated pyrimidine derivative widely used in pharmaceutical and agrochemical synthesis. Key parameters:
| Parameter | Specification | Competitor A | Competitor B |
|---|---|---|---|
| Purity | ≥98% (HPLC) | ≥95% | ≥97% |
| Solubility | DMSO, Ethanol | DMSO only | Limited |
| Storage | 2-8°C, dry | Ambient | 4°C |
2. Applications & Use Cases
Pharmaceutical Intermediates
Used in synthesis of antiviral agents (e.g., HIV protease inhibitors) and kinase inhibitors. Enables precise bromine substitution for targeted molecular modifications.
Agrochemical Development
Key precursor in fungicide formulations, enhancing compound stability against environmental degradation.
Research Applications
Example protocol for Suzuki-Miyaura coupling:
- Mix 1mmol compound with Pd(PPh3)4 catalyst
- React with aryl boronic acid (1.2eq) in THF/H2O
- 85°C, 12h reaction → 92% yield
3. Client Success Stories
Case 1: Top-10 Pharma Company
Challenge: Low yield (48%) in kinase inhibitor intermediate synthesis
Solution: Optimized bromopyrimidine coupling using our compound
Result: 78% yield achieved, reduced production costs by 32%
Case 2: Agrochemical Innovator
Challenge: Field instability of lead fungicide candidate
Solution: Incorporated our compound for structural stabilization
Result: Extended half-life from 14 to 58 days in field trials
4. Contact for Custom Solutions
Request bulk pricing or customized derivatives:
Email: info@vivalr.com
Tel: (86) 15866781826
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