Abstract
This article provides an in-depth overview of 2-Amino-3-hydroxypyridine, a chemical compound with the CAS number 16867-03-1. It delves into its properties, applications, synthesis methods, safety considerations, and its role in various scientific research areas. By the end of the article, readers will have a comprehensive understanding of this compound and its significance in both industrial and academic settings.
Introduction to 2-Amino-3-Hydroxypyridine
2-Amino-3-hydroxypyridine, also known as 2-amino-3-hydroxypyridine, is a pyridine derivative that has gained attention in various scientific fields due to its unique chemical properties. This compound is characterized by the presence of an amino group and a hydroxyl group in the pyridine ring, which makes it versatile for various synthetic applications. In this article, we will explore the must-know facts about 2-Amino-3-Hydroxypyridine CAS 16867-03-1, including its properties, synthesis, applications, and safety considerations.
Chemical Properties of 2-Amino-3-Hydroxypyridine
2-Amino-3-hydroxypyridine is a white crystalline solid that is soluble in water and organic solvents. It has a melting point of approximately 265°C and a boiling point of around 410°C. The compound is stable under normal conditions but can undergo degradation when exposed to strong acids or bases. Its molecular formula is C5H5N2O, and it has a molecular weight of 107.10 g/mol. The presence of the amino and hydroxyl groups in the pyridine ring makes it a potential precursor for the synthesis of various biologically active compounds.
Synthesis of 2-Amino-3-Hydroxypyridine
The synthesis of 2-Amino-3-hydroxypyridine can be achieved through several methods, including the reaction of 2-hydroxypyridine with ammonia or amines, or the reduction of 2-nitro-3-hydroxypyridine. One of the most common synthetic routes involves the reaction of 2-hydroxypyridine with an excess of ammonia in the presence of a catalyst, such as palladium on carbon. This method yields a high purity of the desired compound with good yields.
Applications of 2-Amino-3-Hydroxypyridine
2-Amino-3-hydroxypyridine finds applications in various fields, including pharmaceuticals, agrochemicals, and organic synthesis. In the pharmaceutical industry, it is used as a building block for the synthesis of antiviral and anticancer agents. In agrochemicals, it is employed in the development of herbicides and fungicides. Additionally, its versatile nature makes it a valuable compound in organic synthesis, where it can be used to construct complex molecules with specific functional groups.
Safety Considerations
As with any chemical compound, safety considerations are crucial when handling 2-Amino-3-Hydroxypyridine. The compound is considered hazardous and should be handled with appropriate precautions. It is classified as a skin and eye irritant, and inhalation of its dust or fumes can cause respiratory irritation. Therefore, it is essential to wear protective equipment, such as gloves, goggles, and a lab coat, when working with this compound. Proper ventilation and adherence to safety protocols are also recommended to minimize the risk of exposure.
Role in Scientific Research
2-Amino-3-hydroxypyridine has played a significant role in scientific research, particularly in the fields of medicinal chemistry and organic synthesis. Its unique chemical properties have made it a valuable tool for the development of new drugs and the synthesis of complex organic molecules. Researchers have utilized this compound to study the structure-activity relationships of various compounds and to design novel molecules with potential therapeutic applications.
Conclusion
In conclusion, 2-Amino-3-hydroxypyridine CAS 16867-03-1 is a versatile chemical compound with a wide range of applications in various scientific fields. Its unique chemical properties, synthesis methods, and safety considerations make it an important compound to understand. By exploring the must-know facts about this compound, we gain insight into its significance in both industrial and academic settings. As research continues to evolve, the potential of 2-Amino-3-hydroxypyridine in the development of new drugs and synthetic methodologies remains promising.
Keywords: 2-Amino-3-hydroxypyridine, CAS 16867-03-1, chemical properties, synthesis, applications, safety considerations, scientific research
