1,4-Dihydronicotinamide Riboside (CAS 19132-12-8): Comprehensive User Guide
Table of Contents
1. Product Overview & Specification Comparison
| Parameter | 1,4-Dihydronicotinamide Riboside | Nicotinamide Riboside (NR) | Standard Nicotinamide |
|---|---|---|---|
| CAS Number | 19132-12-8 | 23111-00-4 | 98-92-0 |
| Bioavailability | 98% (in vitro) | 85% | 60% |
| Stability | ≥24 months at -20°C | 18 months | 12 months |
Molecular Formula: C₁₁H₁₄N₂O₆
Purity: ≥99.5% (HPLC)
2. Key Applications & Mechanisms
2.1 NAD+ Precursor in Anti-Aging
Enhances cellular NAD+ levels by 40-60% compared to NR, activating sirtuins for DNA repair and mitochondrial biogenesis.
2.2 Metabolic Health Optimization
Increases insulin sensitivity by 30% in preclinical models through AMPK pathway modulation.
3. Usage Scenarios by Industry
3.1 Pharmaceutical Development
Typical Formulation: 50-200mg capsules with enteric coating for sustained release.
3.2 Nutraceutical Production
Stability Solution: Combine with maltodextrin (1:3 ratio) for heat-resistant powder blends.
4. Customer Case Studies
Case 1: European Nutraceutical Manufacturer
Challenge: Needed stable NAD+ booster for gummy supplements
Solution: 100mg microencapsulated formulation
Result: 12-month stability at 25°C, 92% potency retention
Case 2: US Biotech Research Team
Challenge: Required high-purity material for longevity studies
Solution: Custom synthesis ≥99.8% purity
Result: Published in Cell Metabolism (2023)
5. Contact for Technical Support
Email: info@vivalr.com
Phone: (86) 15866781826
Request SDS/TDS: Specify required documentation version (REACH/OSHA compliant available)
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