Paeonol (CAS 552-41-0): Comprehensive User Guide
Table of Contents
1. Product Overview & Specifications
Paeonol (CAS 552-41-0) is a naturally occurring phenolic compound derived from Paeonia suffruticosa and Cynanchum paniculatum, widely used in pharmaceuticals, cosmetics, and nutraceuticals due to its anti-inflammatory, antioxidant, and neuroprotective properties.
Technical Specifications
| Parameter | Paeonol | Resveratrol | Quercetin |
|---|---|---|---|
| CAS Number | 552-41-0 | 501-36-0 | 117-39-5 |
| Molecular Formula | C9H10O3 | C14H12O3 | C15H10O7 |
| Purity | ≥98% | ≥95% | ≥95% |
| Solubility | Ethanol, DMSO | Ethanol | DMSO |
| Bioavailability | High | Moderate | Low |
2. Key Applications of Paeonol
Pharmaceuticals
- Anti-Arthritis Formulations: Inhibits COX-2 and NF-κB pathways at 10-50 μM concentrations.
- Neuroprotective Agents: Reduces oxidative stress in neuronal cells (IC50: 15 μM).
Cosmeceuticals
- Anti-Aging Creams: 0.2-1.0% concentration improves collagen synthesis by 40%.
- Acne Treatments: Shows 99% antimicrobial activity against Cutibacterium acnes.
3. Usage Guidelines & Best Practices
Pharmaceutical Integration
Step 1: Dissolve in ethanol (1:10 ratio)
Step 2: Mix with excipients at ≤60°C
Optimal Dose: 5-20 mg/kg body weight (in vivo studies)
4. Client Success Stories
Case 1: HerbalCare Pharma (Germany)
- Application: Osteoarthritis gel formulation
- Concentration: 2.5% w/w
- Result: 68% pain reduction in 4-week clinical trial
Case 2: SkinRevive Cosmetics (USA)
- Application: Anti-pollution serum
- Formulation: 0.8% Paeonol + Vitamin C
- Result: 92% customer satisfaction rate
5. Contact for Custom Solutions
Request bulk pricing or formulation support:
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