Ethanesulfonyl Chloride CAS 594-44-5: Comprehensive User Guide
Table of Contents
1. Product Overview & Specifications
CAS Number: 594-44-5
Molecular Formula: C2H5ClO2S
Molecular Weight: 144.58 g/mol
Appearance: Clear colorless to pale yellow liquid
Purity: ≥98% (GC)
Boiling Point: 220°C
Density: 1.406 g/cm3 at 25°C
Comparative Analysis
| Parameter | Ethanesulfonyl Chloride | Methanesulfonyl Chloride | Benzenesulfonyl Chloride |
|---|---|---|---|
| Reactivity | High | Moderate | Low |
| Thermal Stability | Stable up to 200°C | Stable up to 180°C | Decomposes at 150°C |
2. Key Applications & Use Cases
Pharmaceutical Intermediates
Used in synthesizing sulfonamide antibiotics and antiviral agents through nucleophilic substitution reactions.
Agrochemical Production
Key component in creating sulfonylurea herbicides, enhancing crop protection efficiency by 40-60% compared to traditional methods.
3. Industrial Case Studies
Case Study 1: API Manufacturing
Client: Top 10 Global Pharma Company
Challenge: Low yield (52%) in sulfonation step
Solution: Optimized Ethanesulfonyl Chloride ratio (1:1.2 molar ratio)
Result: Yield increased to 89% with 99.5% purity
Case Study 2: Specialty Chemicals
Client: European Chemical Manufacturer
Application: Dye intermediate synthesis
Outcome: Reduced reaction time from 8hr to 2.5hr at 80°C
4. Competitive Advantages
| Feature | Ethanesulfonyl Chloride | Alternatives |
|---|---|---|
| Storage Stability | 24 months under nitrogen | 6-12 months |
| Byproduct Formation | <3% | 8-15% |
5. Request Technical Support
Email: info@vivalr.com
Phone: (86) 15866781826
Request MSDS, COA, or custom synthesis protocols today.
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