Di-tert-butyl Dicarbonate Cas 24424-99-5

Chemical Name: Di-tert-butyl dicarbonate
Synonyms: Di-tert-butyl pyrocarbonate; Dicarbonic acid bis(1,1-dimethylethyl)ester; Pyrocarbonic acid di-tert-butyl ester
CAS No.: 24424-99-5
Molecular Fomula:C10H18O5
Molecular weight: 218.25
Appearance: White crystal powder(Colorless liquid above 23℃)
Assay:≥99.0%

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Di-tert-butyl Dicarbonate (Cas 24424-99-5) Ultimate User Guide 2025

Contents

Product Specifications & Comparative Analysis

Parameter Di-tert-butyl Dicarbonate Alternative Reagents
CAS Number 24424-99-5 N/A
Purity ≥98% (HPLC) 90-95% (Typical competitors)
Storage Temperature 2-8°C (Long-term) Room Temperature (Limited stability)

Applications & Industrial Uses

Primary Functions:

  • Boc-protection of amines in peptide synthesis
  • Intermediate for antiviral drug production
  • Crosslinking agent in polymer chemistry

Operational Guidelines & Safety Protocols

Step-by-Step Handling:

  1. Store under inert atmosphere (Ar/N₂)
  2. Use anhydrous solvents for dissolution
  3. Maintain pH 8-9 during reactions

Case Studies: Pharmaceutical Applications

Case 1: Remdesivir Intermediate Synthesis
Achieved 92% yield improvement through optimized Boc-protection sequences.

Client Success Stories

PharmaTech Co., Ltd (2024):
Reduced production costs by 38% through our bulk supply program (500kg/month).

Request Customized Quotation

Contact our technical team for formulation support:
Email: info@vivalr.com
Tel: (86) 15866781826

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