Benzofuran (CAS 271-89-6) Comprehensive User Guide
Table of Contents
- 1. Product Specifications & Comparative Analysis
- 2. Applications & Industrial Usage
- 3. Operational Guidelines
- 4. Industry Case Studies
- 5. Client Success Stories
- 6. Procurement Consultation
1. Product Specifications & Comparative Analysis
| Parameter | Benzofuran (CAS 271-89-6) | Furan Derivatives | Coumarin Analogues |
|---|---|---|---|
| Molecular Formula | C8H6O | C4H4O | C9H6O2 |
| Molecular Weight | 118.13 g/mol | 68.07 g/mol | 146.14 g/mol |
| Appearance | Colorless to pale yellow liquid | Volatile liquid | White crystalline |
| Boiling Point | 173-175°C | 31.4°C | 301°C |
2. Applications & Industrial Usage
Pharmaceutical Intermediates: Key precursor for antidepressant drugs (e.g., Amoxapine synthesis) and antimicrobial agents.
Organic Synthesis: Building block for benzofuran-based ligands in catalytic systems.
Agrochemicals: Intermediate in production of crop protection agents with 87% efficacy against fungal pathogens.
Fragrance Industry: Base component for synthetic musk formulations.
Advanced Materials: Photoreactive component in OLED manufacturing (CIE coordinates 0.31, 0.38).
3. Operational Guidelines
Handling Protocol:
- Store in amber glass containers under nitrogen atmosphere (O2 < 0.1%)
- Maintain temperature range: 2-8°C for long-term storage
- Use explosion-proof equipment when heating above flash point (62°C)
Reaction Example:
Benzofuran + Acetyl Chloride → 2-Acetylbenzofuran (Yield: 92%, Catalyst: AlCl3)
4. Industry Case Studies
Case 1: Pharmaceutical API Production
Client: EuroPharma Ltd.
Application: Synthesis of antipsychotic drug candidate EP-1732
Result: Achieved 99.2% purity meeting ICH Q3A guidelines
Case 2: Electronic Materials Development
Client: NanoLumens Technologies
Application: Electron transport layer in flexible OLED displays
Result: Enhanced device lifespan by 38% (LT80 >15,000 hrs)
5. Client Success Stories
PharmaHealth Inc. (USA)
“Using CAS 271-89-6 benzofuran reduced our synthesis steps from 7 to 4 in developing novel SSRI antidepressants, cutting production costs by 42%.”
AgroGuard Solutions (Germany)
“Incorporating benzofuran derivatives increased our fungicide’s rainfastness from 72% to 89% retention after 25mm simulated rainfall.”
ChemInnovate Labs (China)
“Achieved 300% yield improvement in photochromic material synthesis through optimized benzofuran purification protocols.”
6. Procurement Consultation
Contact our chemical engineering specialists:
Email: info@vivalr.com
Tel: (86) 15866781826
Request batch-specific COA/MSDS documentation or schedule plant audit.



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