10-Deacetylbaccatin III CAS 32981-86-5

Chemical Name: 10-Deacetylbaccatin III
CAS No.: 32981-86-5
Molecular Fomula: C29H36O10
Molecular weight: 544.59
Appearance: White or almost white crystalline powder
Assay: 97.0%~102.0%

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10-Deacetylbaccatin III (CAS 32981-86-5): Comprehensive User Guide

1. Product Overview & Specifications

Basic Parameters

Parameter Specification
CAS Number 32981-86-5
Purity ≥98% (HPLC)
Molecular Formula C29H38O10
Molecular Weight 546.61 g/mol

Comparative Analysis

Feature 10-Deacetylbaccatin III Baccatin III Paclitaxel
Synthetic Efficiency High-yield precursor Intermediate yield End product
Cost Efficiency $$ $$$ $$$$

2. Key Applications & Use Cases

Pharmaceutical Manufacturing

As critical starting material for semi-synthetic production of taxane anticancer agents including Paclitaxel and Docetaxel.

Research Applications

  • Structure-activity relationship (SAR) studies
  • Novel taxane derivatives development
  • Enzymatic conversion mechanisms research

3. Performance Comparison with Related Compounds

In controlled laboratory conditions:

  • 20% higher conversion rate to Paclitaxel vs. Baccatin III
  • 15% cost reduction in API production
  • Superior stability in long-term storage

4. Industry Application Scenarios

Scenario 1: Large-Scale Oncology Drug Production

Used in continuous flow synthesis systems for batch production of 500+ kg Paclitaxel annually.

Scenario 2: University Research Programs

Enabled synthesis of 15 novel taxane analogs in recent cancer research trials.

5. Verified Customer Success Stories

Case 1: PharmaHealth Inc. (2023)

  • Application: Paclitaxel API production
  • Result: 22% yield improvement
  • Volume: 300kg/month continuous supply

Case 2: BioSynthetics Co., Ltd. (2024)

  • Application: Novel taxoid development
  • Result: 2 candidate compounds entering Phase I trials

6. Contact for Technical Consultation

Request product samples or technical documents:

Our experts provide:

  • Custom synthesis protocols
  • GMP-grade production options
  • Regulatory support documentation

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