6-(1-Bromoethyl)-4-chloro-5-fluoropyrimidine (CAS 188416-28-6) Technical Guide
Table of Contents
- Product Specifications & Comparative Analysis
- Functional Applications
- Operational Guidelines
- Industry Use Cases
- Client Implementations
- Commercial Inquiry
1. Product Specifications & Comparative Analysis
| Parameter | Value |
|---|---|
| CAS Number | 188416-28-6 |
| Molecular Formula | C6H5BrClFN2 |
| Molecular Weight | 239.47 g/mol |
| Appearance | Colorless crystalline solid |
| Solubility | Soluble in organic solvents (alcohols, ethers), insoluble in water |
| Storage | 2-8°C protected environment |
| Density | 1.725±0.06 g/cm³ |
| Boiling Point | 257.8±35.0°C |
2. Functional Applications
This brominated pyrimidine derivative serves as critical intermediate in:
- Pharmaceutical synthesis (Voriconazole API production)
- Quality control reference standard
- Organic reaction catalyst
- Fluorinated compound research
3. Operational Guidelines
Recommended handling protocols:
- Use PPE including nitrile gloves and safety goggles
- Maintain inert atmosphere during reactions
- Store under nitrogen blanket
- Avoid contact with strong oxidizers
4. Industry Use Cases
| Industry | Application |
|---|---|
| Pharmaceuticals | Voriconazole impurity profiling |
| Chemical Research | Halogen exchange reactions |
| Analytical Chemistry | HPLC calibration standard |
5. Client Implementations
Case 1: European Pharma Manufacturer
– Application: Voriconazole process optimization
– Outcome: 22% yield improvement in API synthesis
Case 2: Asian Research Institute
– Application: Fluoropyrimidine derivatives study
– Outcome: Successful development of 3 novel compounds
6. Commercial Inquiry
Contact our technical team for:
- Custom synthesis options
- Bulk pricing (25kg+ quantities)
- Regulatory documentation
Email: info@vivalr.com
Tel: (86) 15866781826



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