4-Hydroxyphenylacetic Acid (CAS 156-38-7) Comprehensive Guide
Table of Contents
- Product Information & Specifications
- Parameter Comparison
- Industrial Applications
- Usage Scenarios
- Client Case Studies
- Contact for Technical Consultation
Product Information & Specifications
| CAS Number | 156-38-7 |
|---|---|
| Molecular Formula | C8H8O3 |
| Molecular Weight | 152.15 g/mol |
| Appearance | White crystalline powder |
| Melting Point | 148-151°C |
| Boiling Point | 346.6°C at 760 mmHg |
| Solubility | 50 g/L in water (20°C) |
| Flash Point | 177.6°C |
Parameter Comparison
| Supplier | Purity | Packaging | Price Range |
|---|---|---|---|
| Shandong Xuchen Chemical | Premium Grade | 25kg/drum | $16.8/kg |
| Jiangsu Pulse Biological | 99% | Customized | Negotiable |
| Beijing North Standards | Analytical Standard | 100mg/vial | $280/vial |
Industrial Applications
Pharmaceutical Intermediate
Essential in synthesizing β-(4-hydroxyphenyl)ethanol (51.2% yield via ester reduction) and active pharmaceutical ingredients including Atenolol impurities and Levothyroxine Sodium impurities.
Antioxidant Agent
Functions as a microbiota-derived polyphenol metabolite with demonstrated radical scavenging properties in biochemical research.
Chemical Synthesis
Precursor for methyl 4-hydroxyphenylacetate (CAS 14199-15-6), used in specialty ester production with melting point 55-58°C.
Usage Scenarios
Quality Control Standards
Validated reference material for HPLC analysis of cardiovascular drugs, meeting pharmacopeia impurity profiling requirements.
Organic Synthesis
Key building block in peptide coupling reactions and chiral compound synthesis for advanced material science applications.
Biochemical Research
Used in gut microbiome studies to quantify phenolic acid metabolites through LC-MS detection methods.
Client Case Studies
Case 1: Pharmaceutical Manufacturer (Shandong, China)
Procured 500kg batch for Atenolol API production, achieving impurity profile compliance with ICH Q3B guidelines. Continuous quarterly orders maintained since Q3 2024.
Case 2: Research Institute (California, USA)
Utilized 4-Hydroxyphenylacetic Acid in longitudinal microbiome study, publishing findings in Nature Metabolism (2024) with 98.7% analytical purity verification.
Case 3: Chemical Distributor (Germany)
Integrated into European supply chain network, supplying 2-5MT monthly to specialty chemical producers with Just-in-Time delivery compliance.
Contact for Technical Consultation
Email: info@vivalr.com
Phone: (86) 15866781826
Request batch-specific COA, MSDS documentation, or discuss bulk procurement terms. Our chemical engineering team provides application support within 24 hours.



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