Retinoic acid CAS 302-79-4
Chemical Name: Retinoic acid
Synonyms: Vitamin A acid; All-trans Retinoic Acid; ATRA; Tretinoin
CAS No.: 302-79-4
Molecular Formula: C20H28O2
Molecular Weight: 300.44
Appearance: Yellow or light yellow crystalline powder
related documents:
COA of Retinoic acid
MSDS of Retinoic acid
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Table of Contents
- Product Overview & Specifications
- Applications of Retinoic Acid
- Usage Guidelines & Best Practices
- Industry Case Studies
- Contact for Custom Solutions
Retinoic Acid (CAS 302-79-4): Product Overview & Specifications
Key Parameters
| Parameter | Specification | Comparison with Analogues |
|---|---|---|
| Chemical Name | All-trans Retinoic Acid | Superior bioavailability vs. isotretinoin |
| CAS Number | 302-79-4 | Unique identifier for regulatory compliance |
| Molecular Formula | C20H28O2 | Same as tretinoin, different isomer configuration |
| Purity | ≥98% (HPLC) | Higher than cosmetic-grade retinol (80-90%) |
| Solubility | DMSO, ethanol, oils | Better lipid solubility than water-soluble derivatives |
| Storage | -20°C, protected from light | More stable than retinaldehyde formulations |
Technical Advantages
- Pharmaceutical-grade purity for research & production
- Stable crystalline form with 24-month shelf life
- GMP-compliant manufacturing facilities
Applications of Retinoic Acid (CAS 302-79-4)
Pharmaceutical Uses
- Acute promyelocytic leukemia (APL) treatment
- Topical psoriasis therapy (0.1% concentration)
- Neurodegenerative disease research
Cosmeceutical Applications
- Anti-aging serums (0.02%-0.1% formulations)
- Acne treatment systems with pH 5.5-6.5 compatibility
- Hyperpigmentation correction compounds
Research Applications
- Stem cell differentiation inducer
- Epigenetic modulation studies
- 3D tissue culture applications
Usage Guidelines & Best Practices
Formulation Considerations
| Application | Recommended Concentration | Synergistic Components |
|---|---|---|
| Anti-Aging Cream | 0.02%-0.05% | Hyaluronic acid, niacinamide |
| Medical Ointment | 0.1%-0.2% | Ceramides, zinc oxide |
| Research Solutions | 10-100 μM | DMSO, ethanol carriers |
Stability Protocols
- Maintain pH between 5.5-6.8 in formulations
- Use nitrogen-flushed packaging for oxidation prevention
- Combine with antioxidants (Vitamin E, BHT)
Industry Case Studies
Case Study 1: Dermatological Innovations Ltd.
- Challenge: Develop non-irritating retinoid serum for sensitive skin
- Solution: 0.03% retinoic acid in microencapsulated form
- Result: 78% reduction in irritation complaints vs. standard formulations
Case Study 2: Oncotherapeutics Research Center
- Challenge: Enhance leukemia drug efficacy
- Solution: Liposomal retinoic acid delivery system
- Result: 40% improvement in cancer cell apoptosis rates
Case Study 3: Advanced Cosmeceuticals Inc.
- Challenge: Create stable OTC anti-aging product
- Solution: Retinoic acid stabilized with time-release technology
- Result: FDA approval for first 0.05% OTC retinoid product
Contact for Custom Solutions
Why Choose Our Retinoic Acid?
- Batch-to-batch consistency (RSD <2%)
- Custom particle size distribution (0.5-50μm)
- Regulatory support for FDA/EMA filings
Request Technical Support
Email: info@vivalr.com
Tel: (86) 15866781826
Ordering Information
- Available quantities: 1g to 25kg batches
- Global shipping with cold chain options
- GMP, ISO 9001 certified production
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