all-trans-Retinol CAS 68-26-8

Chemical Name: all-trans-Retinol
CAS No.: 68-26-8
Molecular Formula: C20H30O
Molecular Weight: 286.45
Appearance: Faded color flaky crystals

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All-Trans-Retinol (CAS 68-26-8) Ultimate Guide for Cosmetic & Pharmaceutical Applications

Table of Contents

1. Product Overview & Specifications

Parameter Specification Testing Method
CAS Number 68-26-8 N/A
Purity ≥98% (Pharma Grade) HPLC
Appearance Yellow Crystalline Powder Visual Inspection
Melting Point 62-64°C DSC
Storage Conditions 2-8°C in Amber Glass ICH Q7

2. Key Applications & Industry Use Cases

2.1 Cosmetic Formulations

– Anti-aging creams (0.1%-1% concentration)
– Acne treatment serums
– Prescription-strength retinoids

2.2 Pharmaceutical Uses

– Topical psoriasis treatments
– Oral vitamin A supplements
– Cancer research applications

3. Technical Comparison Table

Property All-Trans-Retinol Retinyl Palmitate Retinaldehyde
Bioactivity High (Direct precursor) Low (Requires conversion) Medium
Stability ★★★ (Requires antioxidants) ★★★★★ ★★★★
Skin Penetration 85-92% 60-70% 75-80%

4. Real-World Implementation Case Studies

Case 1: Anti-Aging Serum Development

Challenge: Stabilize retinol in water-based formula
Solution: Encapsulation technology + nitrogen packaging
Result: 18-month shelf life at 25°C

Case 2: Prescription Acne Treatment

Challenge: Reduce irritation in 0.5% formulation
Solution: Time-release microspheres
Result: 40% fewer side effects vs. market leaders

5. Client Success Stories

Client 1: ABC Skincare Innovations

Background: EU-based cosmetic manufacturer
Project: Vegan retinol alternative development
Outcome: Achieved 95% efficacy vs. animal-derived retinol

Client 2: HealthDerm Pharmaceuticals

Background: US pharmaceutical company
Project: OTC retinoid cream formulation
Outcome: FDA approval in 11 months

6. Request Customized Solution

Contact our technical team for formulation support:
Email: info@vivalr.com
Phone: (86) 15866781826

Why Choose Us?
– GMP-certified production
– ISO 9001:2015 quality system
– 24/7 technical support
– Global shipping with stability guarantees

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