1-Fluoro-2-nitrobenzene Cas 1493-27-2

Chemical Name: 1-Fluoro-2-nitrobenzene
CAS No.: 1493-27-2
Molecular Fomula: C6H4FNO2
Molecular weight: 141.1
Appearance: Pale yellow clear Liquid
Assay: 99.0%min

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Table of Contents

1. Product Overview & Specifications

1-Fluoro-2-nitrobenzene (CAS 1493-27-2)

Parameter Specification Competitor A Competitor B
Purity ≥99.5% 99.0% 98.8%
Molecular Weight 157.10 g/mol Same Same
Packaging 25kg/drum (nitrogen sealed) 20kg/drum 50kg/drum
Storage Temperature 2-8°C Ambient 0-10°C

2. Key Applications

Pharmaceutical Intermediate

Critical precursor for:

  • Anticancer drug synthesis (e.g., kinase inhibitors)
  • Antibacterial fluorobenzene derivatives

Agrochemical Production

Used in:

  • Herbicide formulations (fluorine-enhanced efficacy)
  • Insecticide intermediates

Material Science

  • Liquid crystal precursor for OLED displays
  • Polymer modification agent

3. Usage Guidelines

Reaction Optimization

Process Recommended Ratio Temperature Range
Nucleophilic Substitution 1:1.2 molar ratio 60-80°C
Catalytic Hydrogenation 1:0.05 (substrate:catalyst) 30-50°C

Safety Protocols

  • Use PPD-compliant respirators during handling
  • Maintain ventilation rate ≥15 air changes/hour

4. Industry Case Studies

Case 1: Pharmaceutical API Manufacturer (Germany)

Challenge: Required high-purity fluorinated intermediate for GMP-grade drug production
Solution: Customized 99.9% purity grade with batch consistency reports
Outcome: 18% yield improvement vs previous supplier

Case 2: Agrochemical Formulator (India)

Challenge: Needed cost-effective fluoronitrobenzene derivative for new herbicide
Solution: Bulk supply with technical support for reaction optimization
Result: Achieved 92% reaction conversion rate

Case 3: Research Institute (USA)

Project: Development of fluorine-containing liquid crystals
Requirement: Small batches with analytical certificates
Success: Enabled publication in Advanced Materials (Impact Factor 30.8)

5. Request Quotation

Contact our technical specialists for:

  • Custom synthesis requirements
  • Bulk pricing (100kg+ orders)
  • Regulatory documentation support

Email: info@vivalr.com
Phone: (86) 15866781826

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