2-Amino-5-Nitrothiazole (CAS 121-66-4) Comprehensive User Guide
Table of Contents
1. Product Overview & Specifications
| Parameter | Value |
|---|---|
| CAS Number | 121-66-4 |
| Molecular Formula | C3H3N3O2S |
| Molecular Weight | 145.14 g/mol |
| Appearance | Yellow crystalline powder |
| Melting Point | 195-200°C (decomposition) |
| Solubility | Sparingly soluble in water (＜0.1 g/100 mL at 20°C), soluble in DMF/DMSO |
| IARC Classification | Group 3 (Not classifiable as carcinogenic) |
2. Key Applications
Dye Intermediate
Primarily used in synthesis of disperse dyes including Disperse Blue 82, 102, 106, 284, and CR/R-Pc series. Enables production of high-performance textile colorants with excellent lightfastness.
Pharmaceutical Intermediate
Critical precursor for antimicrobial agents and antiparasitic drug development. Its nitro-thiazole structure provides bioactivity against anaerobic pathogens.
3. Safety & Handling Guidelines
| Hazard | Precaution |
|---|---|
| Skin Irritation | Wear nitrile gloves and protective clothing |
| Respiratory Risk | Use fume hood for powder handling |
| Thermal Stability | Store below 25°C in sealed containers |
4. Industrial Case Studies
Textile Dye Manufacturing
A European specialty chemicals producer achieved 18% yield improvement in Disperse Blue 106 synthesis through optimized nitration conditions using 2-Amino-5-Nitrothiazole.
5. Verified Client Implementations
Hangzhou Verypharm Chemical Co., Ltd.
Supplies pharmaceutical-grade material for antiparasitic drug R&D programs, maintaining 99.5% purity through HPLC analysis.
6. Request Customized Quotation
For technical specifications, bulk pricing, or SDS documentation:
Email: info@vivalr.com
Tel: (86) 15866781826
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