Table of Contents
Ursodeoxycholic Acid (UDCA) CAS 128-13-2: Product Overview
Key Specifications
| Parameter | Details |
|---|---|
| Chemical Name | Ursodeoxycholic Acid |
| CAS Number | 128-13-2 |
| Molecular Formula | C24H40O4 |
| Purity | ≥98% (HPLC), Pharmaceutical Grade |
| Appearance | White crystalline powder |
| Solubility | Soluble in ethanol (50 mg/ml), slightly soluble in water |
Comparative Analysis
| Grade | Purity | Primary Use | Packaging |
|---|---|---|---|
| Pharmaceutical | ≥98% | Drug formulations | 1kg aluminum foil bags |
| Industrial | ≥95% | Chemical synthesis | 25kg fiber drums |
| Reagent | ≥99% | Research laboratories | 100g glass bottles |
Applications of Ursodeoxycholic Acid
1. Hepatobiliary Diseases Treatment
Clinically used to dissolve cholesterol gallstones and treat primary biliary cholangitis (PBC). Reduces hepatic cholesterol saturation index by 40-60%.
2. Cholesterol Metabolism Regulation
Inhibits intestinal absorption of cholesterol by 25-35% through micelle formation interference.
3. Cosmetic Formulations
Used in anti-aging creams (0.1-0.5% concentration) to enhance skin barrier function.
4. Veterinary Medicine
Treats canine chronic hepatitis at 10-15mg/kg/day dosage.
Usage Cases & Best Practices
Pharmaceutical Manufacturing
Dosage Formulation: Tablet preparation using 250mg UDCA with 1:3 ratio of lactose binder.
Research Applications
In Vitro Studies: Use 10μM concentration in DMEM medium for cholangiocyte protection experiments.
Industrial Synthesis
Chemical Modification: Conversion to taurine conjugate requires 1:1.2 molar ratio in ethanol/water solvent.
Client Case Studies
Case 1: European Pharma Company
| Client | PharmaHealth Inc. (Germany) |
|---|---|
| Requirement | GMP-grade UDCA for PBC treatment drug |
| Solution | Supplied 500kg batches with ≤0.1% lithocholic acid impurity |
| Result | Achieved 99.2% formulation stability over 24 months |
Case 2: Cosmetic Manufacturer
| Client | DermaCare LLC (USA) |
|---|---|
| Requirement | High-purity UDCA for anti-aging serums |
| Solution | Developed micronized form (D90≤10μm) for topical absorption |
| Result | Increased product efficacy by 40% in clinical trials |
Contact for Technical Consultation
Request product samples or discuss custom synthesis requirements:
Email: info@vivalr.com
Tel: (86) 15866781826
Provide your:
- Required quantity (grams to tons)
- Application specifics
- Regulatory compliance needs (USP/EP/JP)
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