N-Methylaniline (CAS 100-61-8) Comprehensive Guide
Table of Contents
- Product Overview & Specifications
- Applications & Industrial Uses
- Safety & Handling Protocols
- Performance Comparison
- Industry Case Studies
- Inquiry & Procurement
Product Overview & Specifications
| Parameter | Value |
|---|---|
| CAS Number | 100-61-8 |
| Molecular Formula | C7H9N |
| Molecular Weight | 107.15 g/mol |
| Appearance | Colorless to reddish-brown oily liquid |
| Melting Point | -57°C |
| Boiling Point | 196.2°C |
| Density | 0.99 g/cm3 |
| Flash Point | 78°C (Closed cup) |
| Solubility | 30 g/L in water, miscible with organic solvents |
Applications & Industrial Uses
N-Methylaniline serves as critical intermediate in:
- Pharmaceutical synthesis (antipyretic/analgesic APIs)
- Dye manufacturing (azo pigments)
- Rubber chemical production (vulcanization accelerators)
- Polymer industry (UV stabilizers)
- Agricultural chemicals (herbicide precursors)
Safety & Handling Protocols
Health Hazards: Causes methemoglobinemia, CNS depression, and hepatorenal toxicity. Chronic exposure leads to anemia and splenomegaly.
First Aid Measures:
- Skin Contact: Flush with water ≥15 minutes
- Eye Exposure: Irrigate with saline ≥30 minutes
- Inhalation: Administer oxygen (4-6 L/min)
Performance Comparison
| Parameter | N-Methylaniline | Aniline |
|---|---|---|
| Acute Toxicity (LD50 oral rat) | 280 mg/kg | 250 mg/kg |
| Vapor Pressure | 0.13 kPa @36°C | 0.67 kPa @25°C |
| Dielectric Constant | 6.2 | 6.89 |
Industry Case Studies
Case 1: European API Manufacturer
Application: Synthesis of paracetamol intermediates
Outcome: 22% yield improvement through optimized methylation
Case 2: Asian Dye Complex
Application: Production of solvent yellow 34
Result: Achieved 99.5% purity with distillation optimization
Inquiry & Procurement
Contact our chemical specialists for:
- Technical specifications
- Custom synthesis options
- Safety documentation
Email: info@vivalr.com
Tel: (86) 15866781826
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