1. Product Overview & Specifications

Ethyl (R)-(+)-2-(4-hydroxyphenoxy)propionate (CAS 71301-98-9) is a chiral compound widely used in asymmetric synthesis. Key specifications include:

Comparative Analysis

2. Key Applications

• Pharmaceutical Intermediates: Synthesis of β-blockers and chiral drugs.
• Agrochemicals: Production of enantioselective herbicides.
• Catalysts: Asymmetric catalysis in organic reactions.
• Research Reagent: Chiral resolution studies.

3. Usage Guidelines

Laboratory Synthesis

For Suzuki-Miyaura coupling: Use 0.1-1 mol% catalyst with 2 eq. of substrate in THF at 60°C for 12h.

Industrial Scale

Optimized conditions: Batch reactors with controlled pH (6.5-7.5) and nitrogen atmosphere.

4. Case Studies

Case 1: Antihypertensive Drug Synthesis

Challenge: Achieve >98% ee in metoprolol intermediate. Solution: Used CAS 71301-98-9 as chiral auxiliary, resulting in 99.2% ee and 85% yield.

Case 2: Herbicide Production

Challenge: Reduce racemization during scale-up. Solution: Implemented low-temperature reaction with CAS 71301-98-9, achieving 97% enantiomeric retention.

5. Client Testimonials

PharmaTech Inc. (USA)

“CAS 71301-98-9 consistently delivered 99%+ ee in our API synthesis, reducing purification costs by 40%.”

AgroSolutions Ltd. (Germany)

“The compound’s stability under industrial conditions enabled seamless scale-up of our chiral herbicide line.”

6. Contact for Queries

For technical specifications or bulk orders:

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Phone: (86) 15866781826

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