2′,4′-Dichloroacetophenone CAS 2234-16-4

1. Product Overview & Specifications

2′,4′-Dichloroacetophenone (CAS 2234-16-4)

Molecular Formula: C₈H₆Cl₂O
Molecular Weight: 189.04 g/mol
Appearance: White to off-white crystalline powder
Purity: ≥98% (HPLC)

Technical Comparison

2. Key Applications

Pharmaceutical Intermediates

Critical precursor in synthesis of antihistamines and CNS drugs, with optimized reaction efficiency in Friedel-Crafts alkylation.

Agrochemical Synthesis

Key component in production of chlorinated pesticide derivatives, demonstrating 18-22% higher yield compared to alternative ketones.

Advanced Material Production

Used in polymer modification for UV-resistant coatings, achieving 95%+ thermal stability at 200°C.

3. Usage Guidelines

Recommended Workflow

1. Pre-dry material at 60°C for 2 hours under vacuum
2. Use inert atmosphere for sensitive reactions
3. Maintain pH between 6.5-7.5 in aqueous systems

Safety Protocols

• PPE Requirement: Neoprene gloves + full face shield
• Storage: Nitrogen-purged containers below 25°C
• Waste Handling: Neutralize with 5% sodium bicarbonate

4. Industry Case Studies

Pharma API Scale-Up

Challenge: Achieve 500kg batch consistency for PDE5 inhibitor intermediate
Solution: Implemented our 99% pure material with controlled particle size distribution
Result: Reduced purification steps by 40%, meeting FDA impurity thresholds

Crop Protection Formulation

Challenge: Develop temperature-stable fungicide concentrate
Solution: Used our low-moisture grade (≤0.3% H₂O)
Result: 12-month shelf stability at 40°C tropical conditions

5. Verified Client Implementations

Top-tier Pharma Company (EU)

Application: Continuous flow synthesis of antipsychotic API
Volume: 2.8MT/year since 2022
Testimonial: “Achieved 92% yield improvement over previous supplier’s material”

Agrochem Leader (USA)

Application: Volume: 650kg/quarter
Outcome: Reduced catalyst loading by 35% while maintaining reaction rate

Specialty Chemical Manufacturer (China)

Application: High-performance epoxy curing agent
Adoption: Full production switch in Q3 2023
Benefit: 15% faster cure time at lower temperatures

6. Request Custom Quote

Contact our technical team for batch-specific analysis reports and volume pricing:

• Email: info@vivalr.com
• Tel: (86) 15866781826

Request following details for faster response:

• Target application sector
• Required purity level
• Annual consumption estimate