Sodium Hyaluronate (CAS 9067-32-7): Comprehensive Technical Guide
Table of Contents
1. Product Specifications & Comparative Analysis
| Parameter | Pharmaceutical Grade | Cosmetic Grade | Food Grade |
|---|---|---|---|
| CAS Number | 9067-32-7 | ||
| Molecular Formula | C14H22NNaO11 | ||
| Molecular Weight | 403.31 g/mol | ||
| Appearance | White crystalline powder | Off-white powder | Translucent granules |
| Purity | ≥99% (HPLC) | ≥95% | ≥98% |
| Molecular Weight Range | 730,000-1,500,000 Da | 10,000-300,000 Da | 5,000-50,000 Da |
| Viscosity (1% solution) | ≥2,000 mPa·s | 500-1,500 mPa·s | 100-400 mPa·s |
2. Functional Applications
2.1 Medical Applications
- Ophthalmic Surgery: Viscoelastic agent for cataract procedures (Healon® equivalent)
- Orthopedics: Intra-articular injections for osteoarthritis management
- Wound Healing: Post-surgical tissue regeneration accelerator
2.2 Cosmetic Formulations
- Anti-aging serums with 0.1-1.0% concentration
- Dermal filler formulations (cross-linked variants)
- Liposome-encapsulated delivery systems
2.3 Advanced Drug Delivery
- Ocular drug retention enhancer (3-5x bioavailability improvement)
- Targeted cancer therapy via CD44 receptor binding
- Controlled-release matrix for NSAIDs
3. Implementation Case Studies
3.1 Orthopedic Solution
Application: 12-week clinical trial with 2% sodium hyaluronate injection
Results: 68% reduction in WOMAC pain scores (n=120 patients)
3.2 Premium Skincare Line
Formulation: 0.8% low-MW HA in nano-emulsion
Performance: 24-hour hydration retention (corneometer measurements)
4. Verified Client Success Stories
4.1 Shandong Haiwoo Biotechnology
Project: GMP-certified production line for ophthalmic-grade HA
Capacity: 500kg/month with ISO 13485 compliance
4.2 YuanMeng Bio-Tech
Innovation: Hybrid HA-chitosan wound dressing
Commercialization: CE Mark obtained Q3 2024
5. Request Customized Solutions
Contact our technical team for formulation support and bulk pricing:
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