chlorogenic acid cas 327-97-9

Chemical Name:Chlorogenic acidCAS: 327-97-9Molecular Fomula:C16H18O9Molecular Weight:354.31
Appearance: Light Yellow Brown powder
Assay:50%

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Table of Contents

Chlorogenic Acid (CAS 327-97-9) Technical Specifications

Core Parameters

Parameter Specification
Chemical Name 5-O-Caffeoylquinic acid
CAS Number 327-97-9
Molecular Formula C16H18O9
Molecular Weight 354.31 g/mol
Appearance Off-white to light yellow powder
Purity 50%-98% (HPLC)
Solubility Water soluble (hot water), ethanol soluble

Grade Comparison

Feature Food Grade Pharma Grade Cosmetic Grade
Purity ≥50% ≥95% ≥70%
Heavy Metals <10ppm <5ppm <8ppm
Certifications ISO, FDA GMP, USP ECOCERT

Industrial Applications Analysis

Nutraceutical Applications

Chlorogenic acid demonstrates hypoglycemic effects by inhibiting glucose-6-phosphatase (IC50 = 3.2μM). Clinical studies show 400mg/day supplementation reduces postprandial glucose spikes by 15-22%.

Pharmaceutical Formulations

Used in hypertension management through ACE inhibition (30-45% inhibition at 100μg/mL concentrations). Patent EP1980254 details sustained-release formulations for cardiovascular applications.

Cosmeceutical Innovations

Shows 89% tyrosinase inhibition at 0.5% concentration (superior to 72% for arbutin). Market leader L’Oréal utilizes CGA in 18+ anti-aging products since 2020.

Implementation Case Studies

Case 1: Functional Food Development

A European manufacturer achieved 23% market share increase using our 70% CGA in green coffee bean extract capsules. Formulation: 200mg CGA + 50mg chromium picolinate per serving.

Case 2: Advanced Drug Delivery

Pharma client enhanced bioavailability by 40% using our nano-encapsulated 98% CGA (particle size 150-200nm). Achieved 8-hour sustained release profile in preclinical trials.

Verified Client Success Stories

Client A: Global Supplement Brand

Parameter Details
Industry Dietary Supplements
Application Weight Management Formulas
Usage Level 300mg/day standardized extract
Result 23% improvement in fat metabolism markers

Client B: Topical Formulator

Parameter Details
Industry Cosmetic Science
Application Anti-Pigmentation Serum
Formula 2% CGA + 1% niacinamide
Clinical Result 34% melanin reduction in 8 weeks

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Our experts provide:

  • Formulation optimization
  • Analytical method development
  • Regulatory compliance consulting

Contact Our Team

Email: info@vivalr.com
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Why Choose Us?

  • ISO 9001-certified production
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