Table of Contents
- Sofosbuvir (CAS 1190307-88-0) Overview
- Specification Comparison
- Usage Scenarios
- Client Success Stories
- Contact for Custom Solutions
Sofosbuvir (CAS 1190307-88-0) Overview
Key Specifications
| Parameter | Detail |
|---|---|
| CAS Number | 1190307-88-0 |
| Chemical Name | Isopropyl (2S)-2-[[[(2R,3R,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-4-fluoro-3-hydroxy-4-methyl-tetrahydrofuran-2-yl]methoxy-phenoxy-phosphoryl]amino]propanoate |
| Molecular Formula | C₂₂H₂₉FN₃O₉P |
| Molecular Weight | 529.45 g/mol |
| Appearance | White to off-white crystalline powder |
Specification Comparison
| Vendor | Purity | Price/kg | Lead Time | Certifications |
|---|---|---|---|---|
| VIVALR Standard | ≥99.5% | $XX,XXX | 2-4 weeks | GMP, DMF |
| Competitor A | ≥98.0% | $XX,XXX | 6-8 weeks | CEP |
| Competitor B | ≥99.0% | $XX,XXX | 4-6 weeks | USP |
Detailed Applications
Pharmaceutical Applications
As key component in:
- HCV NS5B polymerase inhibitors
- Combination therapies with ledipasvir/velpatasvir
- Generic antiviral formulations
Research Applications
- Viral replication mechanism studies
- Nucleotide analog comparative research
- Drug resistance profiling
Usage Scenarios
Manufacturing Process
Typical batch size: 50-200kg
Solvent system: Acetonitrile/water gradient
Purification: Chromatography ≥95% recovery rate
Formulation Development
Compatibility with:
– PEG matrices
– Enteric coatings
– Co-crystal engineering
Client Success Stories
Case 1: Indian Generic Manufacturer
Client Profile: Top 10 generic producer
Challenge: Needed 500kg GMP-grade material in 8 weeks
Solution: Accelerated production + air freight coordination
Outcome: Met WHO prequalification timeline
Case 2: European Research Consortium
Client Profile: EU-funded antiviral project
Requirement: 10kg research-grade with custom analytical data
Solution: Tailored QC package + stability studies
Result: Enabled 6-month accelerated publication
Case 3: US Biotech Startup
Client Profile: Novel combination therapy developer
Need: Small batches (5-20kg) with rapid turnaround
Service: Flexible scheduling + real-time tracking
Achievement: Reduced preclinical phase by 11 weeks
Contact for Custom Solutions
Request tailored quotations:
Email: info@vivalr.com
Phone: (86) 15866781826
Technical consultation available M-F 08:00-18:00 GMT+8
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