Comprehensive Guide to Sodium Thiosulfate Pentahydrate (CAS 10102-17-7)
Table of Contents
- Product Specifications & Comparative Analysis
- Industrial & Clinical Applications
- Operational Case Studies
- Client Implementation Scenarios
- Safety Protocols & Compliance
- Technical Consultation & Procurement
1. Product Specifications & Comparative Analysis
| Parameter | Pentahydrate Form | Anhydrous Form |
|---|---|---|
| Molecular Formula | Na2S2O3·5H2O | Na2S2O3 |
| CAS Registry | 10102-17-7 | 7772-98-7 |
| Molecular Weight | 248.18 g/mol | 158.11 g/mol |
| Appearance | Colorless monoclinic crystals | White crystalline powder |
| Water Solubility (20°C) | 680 g/L | 700 g/L |
| Thermal Profile | Melts at 48°C, decomposes at 100°C | Stable up to 220°C |
2. Industrial & Clinical Applications
2.1 Medical Therapeutics
- Cyanide antidote: Chelates cyanide ions to form non-toxic thiocyanate
- Oncology support: Reduces cisplatin-induced ototoxicity in pediatric patients
- Dermatological applications: Manages calciphylaxis lesions in dialysis patients
2.2 Industrial Utilization
- Water treatment: Chlorine neutralization in municipal systems
- Photographic processing: Fixing agent for silver halide dissolution
- Analytical chemistry: Iodometric titration standard
3. Operational Case Studies
3.1 Pharmaceutical Application
Challenge: Mitigating cisplatin-associated hearing loss (≥20 dB) in children with hepatoblastoma
Solution: 16-hour post-chemotherapy infusion at 20g/m²
Outcome: 68.9% relative risk reduction in ototoxicity (P=0.00022)
3.2 Water Treatment Implementation
Challenge: Residual chlorine removal in 50MGD wastewater plant
Solution: Automated dosing system maintaining 2.5ppm residual
Outcome: 99.8% dechlorination efficiency achieved
4. Client Implementation Scenarios
4.1 TargetMol Research Solutions
- Application: Antioxidant studies in neurodegenerative models
- Specifications: 99.99% purity, T65440 batch certification
- Result: 40% reduction in oxidative markers at 5mM concentration
4.2 MedChemExpress Clinical Trials
- Application: Calciphylaxis treatment protocol development
- Dosage: 25g/L topical solution, twice daily application
- Outcome: 52% wound size reduction in 12-week trial
5. Safety Protocols & Compliance
| Parameter | Specification |
|---|---|
| OSHA PEL | 5mg/m³ (8-hour TWA) |
| Ecotoxicity | LC50 (96h): 120mg/L (Rainbow trout) |
| Storage | 2-8°C in sealed desiccators |
| Decomposition | Releases SOx fumes above 100°C |
6. Technical Consultation & Procurement
For technical specifications or commercial inquiries:
Email: info@vivalr.com
Phone: (86) 15866781826
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