Chlorosulfonyl Isocyanate CAS 1189-71-5
Chemical Name: Chlorosulfonyl isocyanate
Synonyms: Chlorosulfonic acid isocyanate; N-Chlorosulphonyl isocyanate; Sulfonyl chloride isocyanate
CAS No.: 1189-71-5
Molecular Fomula: CClNO3S
Molecular weight: 141.53
Appearance: Colorless transparent liquid
Assay: 99.2%min
Chlorosulfonyl Isocyanate (CAS 1189-71-5): Technical Guide & Applications
Table of Contents
1. Product Specifications
| Parameter | Value |
|---|---|
| CAS Number | 1189-71-5 |
| Molecular Formula | CClNO3S |
| Molecular Weight | 141.53 g/mol |
| Appearance | Clear liquid |
| Density (25°C) | 1.626 g/mL |
| Boiling Point | 107°C |
| Flash Point | 18.5°C |
| Water Solubility | Reacts exothermically |
2. Key Applications
Organic Synthesis
- Electrophilic aromatic substitution for nitrile production
- Synthesis of carbamates via reactions with alcohols/phenols
- Heterocyclic compound preparation through alkene/alkyne additions
Pharmaceutical Intermediates
- Production of sulfonamide-based drug candidates
- Functional group transformation in API development
3. Operational Guidelines
Safety Protocols
- Use corrosion-resistant equipment (glass/PTFE-lined)
- Maintain inert atmosphere (N2/Ar) during reactions
- Cooling required for exothermic processes
Storage Requirements
- Temperature: 2-8°C in sealed containers
- Separate from water sources and alkaline materials
4. Industrial Case Studies
Case 1: Pharmaceutical Intermediate Production
Client: Wuhan Provo Biotechnology
Application: Synthesized novel sulfonamide antibiotics
Outcome: Achieved 92% yield with 99.5% purity
Case 2: Specialty Chemical Manufacturing
Client: Hubei Tuobang Chemical
Application: Developed flame-retardant additives
Outcome: Reduced production costs by 18%
5. Supplier Comparison
| Supplier | Purity | Packaging | MOQ |
|---|---|---|---|
| Jinan Shengqi Pharma | ≥99% | 25kg/drum | 1kg |
| Shanghai Fuzhe Chemical | ≥99.5% | Customized | 100g |
| Hubei Tuobang | 99% | 160-220kg drums | 1kg |
6. Contact for Custom Solutions
Request technical datasheets or discuss bulk procurement:
- Email: info@vivalr.com
- Tel: (86) 15866781826
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