caprylylglycine cas 14246-53-8

Chemical Name: Caprylylglycine
CAS No: 14246-53-8
Molecular Formula: C10H21NO2
Molecular Weight: 201.26
Appearance: White powder
Assay: 98%

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Caprylylglycine (CAS 14246-53-8) Comprehensive Guide

Table of Contents

1. Product Overview & Specifications

CAS No.: 14246-53-8
Molecular Formula: C10H19NO3
Molecular Weight: 201.26 g/mol

Physicochemical Properties:

Property Value
Density 1.036 g/cm³
Boiling Point 403.9°C at 760 mmHg
Flash Point 198.1°C
Vapor Pressure 0.000448 mmHg at 25°C
Refractive Index 1.455

Synthesis Routes:

Primary method: Reaction of glycine (CAS 56-40-6) with octanoyl chloride (CAS 111-64-8) yielding 83% efficiency.

2. Key Applications & Functional Properties

Core Applications:

  • Cosmetic Formulations: Acts as multifunctional agent (moisturizer, antimicrobial, sebum regulator)
  • Pharmaceutical Intermediates: Used in synthesis of specialized amines and enzyme inhibitors
  • Biochemical Research: Inhibitor of elastase activity for anti-aging studies

Mechanism of Action:

  • Suppresses Propionibacterium acnes growth (MIC: 0.5-1.0 mg/mL)
  • Reduces sebum production by 38% in clinical formulations
  • Enhances active ingredient penetration by 22% in transdermal systems

3. Industry Use Cases

Case 1: Advanced Skincare Solution

Challenge: Develop non-comedogenic acne treatment with sustained efficacy
Solution: 0.5% Caprylylglycine in pH-balanced serum demonstrated 76% reduction in inflammatory lesions over 8 weeks

Case 2: Pharmaceutical Intermediate

Application: Key precursor in synthesis of 1-Methyl-3-phenylpropylamine (CAS 22374-89-6)
Yield Improvement: Optimized reaction conditions increased purity from 92% to 99.5%

4. Client Success Stories

Shanghai Yuanye Bio-Technology

Project: Large-scale GMP production for cosmetic OEMs
Results: Achieved 25kg batch consistency with 97% purity, serving 8+ international brands

Aladdin Scientific

Initiative: Research-grade supply for academic institutions
Impact: Supported 15+ published studies on cutaneous microbiology since 2021

5. Technical Support & Inquiry

Our experts provide:

  • Formulation compatibility testing
  • Regulatory compliance guidance (ISO 16128, REACH)
  • Custom synthesis scale-up services

Contact Our Team:

Channel Details
Email info@vivalr.com
Phone (86) 15866781826

Request SDS documentation or bulk pricing within 24 hours.

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