D-Serine (CAS 312-84-5) Technical Guide
Table of Contents
1. Product Overview & Specifications
| Parameter | D-Serine | L-Serine (Comparison) |
|---|---|---|
| CAS Number | 312-84-5 | 56-45-1 |
| Molecular Formula | C3H7NO3 | C3H7NO3 |
| Molecular Weight | 105.09 g/mol | 105.09 g/mol |
| Melting Point | 220°C | 228°C |
| Water Solubility (20°C) | 346 g/L | 360 g/L |
| Optical Rotation [α]D20 | -14.75° (c=10 in 2N HCl) | +14.0° to +15.6° |
Key Properties: White crystalline powder, chiral purity >99%, pH 5.5-6.5 (1% aqueous solution). Store at room temperature in airtight containers.
2. Key Applications
Pharmaceuticals
- NMDA receptor agonist for neurological research
- Intermediate in lacosamide production
- Cell culture media component
Industrial Uses
- Chiral building block for asymmetric synthesis
- Reference standard in analytical chromatography
- Biochemical studies of purine/pyrimidine metabolism
3. Usage Guidelines
Handling Precautions
- Use PPE (gloves, goggles) to prevent eye/skin contact
- Avoid dust formation – handle in fume hood
- Incompatible with strong oxidizers
Solution Preparation
- Dissolve in deionized water at ≤50°C
- Filter through 0.22μm membrane for sterile applications
- Adjust pH with HCl/NaOH as required
4. Industry Case Studies
Case 1: Neurological Research (2024)
Client: Shanghai Institute of Neuroscience
Application: 500g D-Serine used in NMDA receptor activation studies, achieving 98.5% purity via HPLC validation.
Case 2: Pharmaceutical Production
Client: Wuhan Hezhong Biotech
Application: 25kg batch utilized in lacosamide intermediate synthesis, yielding 92.3% reaction efficiency.
5. Supplier Comparison
| Supplier | Purity | Packaging | Price (USD) |
|---|---|---|---|
| Leyan (Shanghai) | 98% | 100g | $53.00 |
| Nanjing Duly | 99% | 25g | $130.00 |
| Zhengzhou Huawen | 99.5% | 1kg | $1,450.00 |
6. Contact for Quotation
Request custom formulations or bulk pricing:
Email: info@vivalr.com
Tel: (86) 15866781826



评论
目前还没有评论。