1,1,3,3-tetramethylguanidine cas 80-70-6

Appearance: Colorless transparent liquid
Assay: 99%min
Packing: 180kg/drum
Capacity: 1000MT/year
Sample: Available

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Table of Contents

1,1,3,3-Tetramethylguanidine (CAS 80-70-6): Technical Specifications

Basic Properties

Parameter Specification
Chemical Name 1,1,3,3-Tetramethylguanidine
CAS Number 80-70-6
Molecular Formula C5H13N3
Molecular Weight 115.18 g/mol
Appearance Colorless to pale yellow liquid
Purity ≥99% (GC analysis)
Density 0.92 g/cm³ at 20°C
Boiling Point 160-162°C

Performance Comparison

Feature TMG DBU MTBD
Basicity (pKa) 13.5 11.5 14.0
Reaction Speed Fast Moderate Very Fast
Thermal Stability Excellent Good Excellent
Price Competitiveness $$ $$$ $$$$

2. Industrial Applications & Functional Advantages

Pharmaceutical Synthesis

Preferred catalyst for nucleophilic substitution reactions in API production, particularly effective in:

  • Beta-lactam antibiotic synthesis
  • Heterocyclic compound formation
  • Peptide coupling reactions

Polymer Chemistry

  • Polyurethane catalyst showing 40% faster curing vs conventional amines
  • Epoxy resin modifier enhancing thermal resistance

3. Documented Client Implementations

Case 1: Pharmaceutical Intermediate Production

Client Top 10 EU Pharma Manufacturer
Challenge Low yield (58%) in cephalosporin intermediate synthesis
Solution 0.8mol% TMG catalyst system
Result Yield increased to 89% with 99.2% purity

Case 2: Specialty Adhesive Development

Client US Aerospace Materials Supplier
Application High-temperature polyimide adhesives
Benefit Enabled 300°C operational stability
Volume 2.5MT annual consumption

4. Safety & Regulatory Compliance

Aspect Requirement
Storage Nitrogen atmosphere, <25°C
PPE Chemical goggles + neoprene gloves
Spill Management Absorb with vermiculite, pH neutralization
Transport UN2922 Corrosive liquid, toxic

5. Technical Consultation & Ordering

Contact our chemical engineers for application-specific guidance:

Email: info@vivalr.com
Tel: (86) 15866781826

Request:

  • Custom purity specifications (99.5%-99.99%)
  • Bulk packaging solutions (200kg drums to ISO tanks)
  • REACH-compliant documentation
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