1. Product Overview & Specifications

2. Key Applications

Organic Synthesis

• Phosphine Ligand Precursor: Synthesizes chiral ligands (e.g., diphenylarylphosphines) for asymmetric catalysis.
• Wittig-Horner Reagent: Generates α,β-unsaturated carbonyl compounds via olefination reactions.
• Fluorinated Compound Synthesis: Reacts with ClCF₂CO₂Et to produce difluoromethyl derivatives.

Polymer Chemistry

• Flame Retardant Intermediate: Used in halogen-free flame retardants for engineering plastics.
• OLED Material Production: Key precursor for electronic materials in display technologies.

3. Operational Guidelines

Reaction Optimization

• Catalytic Additions: Use transition metal catalysts (e.g., Pd, Cu) for stereospecific alkyne/alkene additions.
• Solvent-Free Reactions: Microwave-assisted reactions achieve 85–92% yield without solvents.

Purification

• Recrystallize from ethanol/water mixtures (3:1 ratio).
• Chromatographic purification using silica gel (hexane/ethyl acetate).

4. Industry Case Studies

Case 1: Flame Retardant Development

Client: Major Japanese Chemical Manufacturer
Application: Halogen-free flame retardant for polyamide 6.6
Result: Achieved UL94 V-0 rating with 18% loading; reduced smoke emission by 40%.

Case 2: Pharmaceutical Intermediate Synthesis

Client: Application: Synthesis of kinase inhibitor intermediates
Result: Improved reaction yield from 68% to 89% using DPO-mediated Horner-Wadsworth-Emmons reaction.