Trimethoprim (CAS 738-70-5): Comprehensive Product Guide
Table of Contents
1. Product Overview & Specifications
Basic Information
| Parameter | Details |
|---|---|
| CAS Number | 738-70-5 |
| Molecular Formula | C14H18N4O3 |
| Molecular Weight | 290.32 g/mol |
| Appearance | White to off-white crystalline powder |
| Melting Point | 199–203°C |
| Solubility | Soluble in DMSO, chloroform; slightly soluble in ethanol; insoluble in water |
| Storage | 2–8°C, protected from light |
2. Key Applications
Pharmaceutical Industry
Trimethoprim is widely used as an antibacterial synergist, enhancing the efficacy of sulfonamide antibiotics in treating urinary tract infections, respiratory infections, and gastrointestinal disorders.
Veterinary Medicine
In animal health, it serves as a critical component in combating bacterial infections and coccidiosis in livestock, poultry, and aquaculture.
Research & Development
As a reference standard (HPLC ≥98%), it supports drug discovery, pharmacokinetic studies, and quality control in laboratories.
3. Usage Scenarios
Human Therapeutics
Combined with sulfamethoxazole, Trimethoprim forms co-trimoxazole, a first-line treatment for Pneumocystis pneumonia in immunocompromised patients.
Poultry Farming
At 0.02–0.04% concentration in feed, it prevents outbreaks of E. coli and Salmonella, improving livestock survival rates.
4. Customer Case Studies
Case 1: Pharmaceutical Manufacturer (Hubei, China)
A leading API producer uses Trimethoprim (99% purity) to formulate combination therapies, achieving 30% faster production cycles through optimized solubility profiles.
Case 2: Veterinary Research Institute (Shanghai)
Researchers reduced poultry mortality by 45% using Trimethoprim-supplemented feed, validated through a 12-month trial across 10,000 birds.
5. Inquiry & Contact
Customized solutions available: Bulk quantities (25 kg drums), HPLC-grade standards, and veterinary formulations.
| Contact Method | Details |
|---|---|
| info@vivalr.com | |
| Phone | (86) 15866781826 |



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