Comprehensive Guide to 6-Bromo-2-methylquinoline: Applications, Case Studies & Purchasing Insights
Table of Contents
1. Product Overview & Specifications
| Parameter | Specification |
|---|---|
| CAS Number | 102085-46-3 |
| Molecular Formula | C10H8BrN |
| Molecular Weight | 222.08 g/mol |
| Appearance | Off-white crystalline powder |
| Purity (HPLC) | ≥98.5% |
| Melting Point | 112-115°C |
| Storage Conditions | 2-8°C in airtight container |
2. Industrial Applications & Use Cases
Key Application Areas:
- Pharmaceutical intermediates for kinase inhibitors
- OLED material precursor development
- Coordination chemistry ligands
- Antimicrobial agent research
3. Technical Performance Comparison
| Parameter | 6-Bromo-2-methylquinoline | Similar Compounds |
|---|---|---|
| Reactivity | High bromine substitution activity | Lower in non-brominated analogs |
| Thermal Stability | Stable up to 200°C | Varies by substituents |
| Synthetic Yield | 85-92% (optimized routes) | Typically 70-85% |
4. Case Study 1: Pharmaceutical Intermediate Synthesis
Client: European Pharma Research Consortium
Application: Key precursor in tyrosine kinase inhibitor development
Scale: 150kg/month production
Result: 22% improvement in reaction yield vs previous intermediates
5. Case Study 2: OLED Material Development
Client: Asian Electronic Materials Manufacturer
Application: Electron transport layer component
Spec Achievement: Enhanced device lifetime by 15%
Purity Requirement: 99.9% for commercial batches
6. Procurement Considerations & Supplier Evaluation
Quality Assurance Checklist:
- Batch-to-batch consistency reports
- Residual solvent analysis
- Stability testing documentation
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