6-CHLORONICOTINOYL CHLORIDE

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6-Chloronicotinoyl Chloride: Comprehensive Product Guide

Table of Contents

1. Product Overview & Specifications

Parameter 6-Chloronicotinoyl Chloride Similar Compounds
CAS Number 101588-91-4 Varies by derivative
Molecular Formula C6H3Cl2NO Depends on substitution
Purity ≥98% (HPLC) Typically 95-99%
Appearance White crystalline powder Similar physical form
Storage Conditions 2-8°C in airtight container Comparable requirements

2. Key Applications & Uses

6-Chloronicotinoyl chloride serves as critical intermediate in:

  • Pharmaceutical synthesis (CNS drugs, antiviral agents)
  • Agrochemical production (neonicotinoid insecticides)
  • Material science research (coordination complexes)
  • Organic electronics precursor development

3. Performance Comparison

Feature 6-Chloronicotinoyl Chloride Nicotinoyl Chloride 2-Chloroisonicotinoyl Chloride
Reactivity High electrophilicity Moderate Selective
Stability Moisture-sensitive Similar profile More stable
Synthetic Yield 85-92% 78-85% 80-88%

4. Usage Scenarios

Pharmaceutical Intermediate

Used in 3-step synthesis of Abametapir (USAN approved antiparasitic agent):

  1. Initial coupling reaction at -15°C
  2. Controlled hydrolysis process
  3. Final purification via column chromatography

5. Client Case Studies

Case 1: European Pharma Company

  • Application: Antiviral drug intermediate
  • Volume: 150kg/month
  • Result: 18% yield improvement vs previous synthesis route

Case 2: Asian Agrochem Producer

  • Application: Next-gen insecticide development
  • Technical Support: Custom purity optimization
  • Outcome: Achieved 99.2% purity for regulatory submission

6. Inquiry & Consultation

Contact our technical team for:

  • Custom synthesis requirements
  • Bulk pricing (50kg+ quantities)
  • Technical documentation support

Email: info@vivalr.com
Phone: (86) 15866781826

Why Choose Us:
• ISO 9001-certified production
• 24/7 technical support
• Flexible packaging solutions
• Global logistics network

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